Hao Ran Zhang, Jia Wei Wu, Lecong Wang, Ming Zhu Ye, Guo Hua Zheng
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引用次数: 0
摘要
本研究旨在调查认知储备（CR）对社区老年人体育锻炼与认知功能之间关系的中介作用。这项横断面研究共纳入了 495 名居住在社区的老年人。研究评估了认知储备、认知功能、体育锻炼和潜在的混杂因素。研究人员使用回归分析和引导分析来探讨 CR 在体育锻炼和认知功能中的中介作用。与中低体力活动量的老年人相比，在调整了混杂因素后，高体力活动量的老年人的整体认知功能（βMoCA 评分 = 1.22，95% CI 0.41 ~ 2.04）和视觉空间功能（βCDT 评分 = 0.52，95% CI 0.11 ~ 0.94）明显更好。在对混杂因素进行调整后，CR 在体育锻炼与认知功能之间起着中介作用，对总体认知功能（βMoCAscores = -0.29，95% CI -0.56~-0.09）和视觉空间功能（βCDTscores = -0.14，95% CI -0.28~-0.05）有间接影响，中介比例分别为 23.8%和 26.7%。这些研究结果表明，大量体育锻炼可有效增加社区老年人的认知储备，保持或改善认知功能。
Mediating Effect of Cognitive Reserve in the Relationship Between Physical Activity and Cognitive Function in Community-Dwelling Older Adults.
The aim of this study was to investigate the mediating effect of cognitive reserve (CR) on the association between physical activity and cognitive function in community-dwelling older adults. A total of 495 community-dwelling older adults were included in this cross-sectional study. The CR, cognitive function, physical activity, and the potential confounders were assessed. Regression and bootstrap analyses were used to explore the mediating role of CR in physical activity and cognitive function. Compared to older adults with low to moderate physical activity, older adults with high physical activity had significantly better global cognitive function (βMoCA scores = 1.22, 95% CI 0.41 ~ 2.04) and visual spatial function (βCDT scores = 0.52, 95% CI 0.11 ~ 0.94) after adjustment for the confounders. CR mediated the association between physical activity and cognitive function with an indirect effect for global cognitive function (βMoCAscores = -0.29, 95% CI -0.56 ~ -0.09) and visual spatial function (βCDTscores = -0.14, 95% CI -0.28 ~ -0.05) after adjusting for the confounders, with 23.8% and 26.7% as percentage of mediation, respectively. These findings suggest that high physical activity could be effective in increasing cognitive reserve and preserving or improving cognitive function in community-dwelling older adults.
期刊介绍：
Experimental Aging Research is a life span developmental and aging journal dealing with research on the aging process from a psychological and psychobiological perspective. It meets the need for a scholarly journal with refereed scientific papers dealing with age differences and age changes at any point in the adult life span. Areas of major focus include experimental psychology, neuropsychology, psychobiology, work research, ergonomics, and behavioral medicine. Original research, book reviews, monographs, and papers covering special topics are published.
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