{"title":"蛋白质组学证据表明,种子气味改变了散食性动物的嗅觉和空间记忆。","authors":"Xiangyu Zhao, Yingnan Wang, Xianfeng Yi","doi":"10.1016/j.bbr.2024.115282","DOIUrl":null,"url":null,"abstract":"<div><div>Seed odor plays a crucial role in affecting the scatter-hoarding behavior of small rodents that rely on spatial memory and olfaction to cache and recover. However, evidence of how seed odor modifies olfaction function and spatial memory is still lacking. Here, we coated seeds with waterproof glue to test how seed odor intensity alters the proteome of both the olfactory bulbs and hippocampus of a dominant scatter-hoarding rodent, <em>Leopoldamys edwardsi,</em> in Southwest China. We showed that animals repeatedly caching and recovering weak odor seeds exhibited greater olfactory ability and spatial memory, as indicated by alterations in the protein profiles of the olfactory bulbs and hippocampus. The upregulation of proteins closely related to neural connections between the olfactory bulb and hippocampus is highly responsible for improved olfactory function and spatial memory. Our study provides new insights into how scatter-hoarding rodents manage and respond to cached seeds differing in odor intensity from a neurobiological perspective, which is of significant importance for better understanding the parallel evolution of the olfactory and hippocampal systems.</div></div>","PeriodicalId":8823,"journal":{"name":"Behavioural Brain Research","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Proteomic evidence for seed odor modifying olfaction and spatial memory in a scatter-hoarding animal\",\"authors\":\"Xiangyu Zhao, Yingnan Wang, Xianfeng Yi\",\"doi\":\"10.1016/j.bbr.2024.115282\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Seed odor plays a crucial role in affecting the scatter-hoarding behavior of small rodents that rely on spatial memory and olfaction to cache and recover. However, evidence of how seed odor modifies olfaction function and spatial memory is still lacking. Here, we coated seeds with waterproof glue to test how seed odor intensity alters the proteome of both the olfactory bulbs and hippocampus of a dominant scatter-hoarding rodent, <em>Leopoldamys edwardsi,</em> in Southwest China. We showed that animals repeatedly caching and recovering weak odor seeds exhibited greater olfactory ability and spatial memory, as indicated by alterations in the protein profiles of the olfactory bulbs and hippocampus. The upregulation of proteins closely related to neural connections between the olfactory bulb and hippocampus is highly responsible for improved olfactory function and spatial memory. Our study provides new insights into how scatter-hoarding rodents manage and respond to cached seeds differing in odor intensity from a neurobiological perspective, which is of significant importance for better understanding the parallel evolution of the olfactory and hippocampal systems.</div></div>\",\"PeriodicalId\":8823,\"journal\":{\"name\":\"Behavioural Brain Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-10-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Behavioural Brain Research\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0166432824004388\",\"RegionNum\":3,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BEHAVIORAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioural Brain Research","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0166432824004388","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BEHAVIORAL SCIENCES","Score":null,"Total":0}
Proteomic evidence for seed odor modifying olfaction and spatial memory in a scatter-hoarding animal
Seed odor plays a crucial role in affecting the scatter-hoarding behavior of small rodents that rely on spatial memory and olfaction to cache and recover. However, evidence of how seed odor modifies olfaction function and spatial memory is still lacking. Here, we coated seeds with waterproof glue to test how seed odor intensity alters the proteome of both the olfactory bulbs and hippocampus of a dominant scatter-hoarding rodent, Leopoldamys edwardsi, in Southwest China. We showed that animals repeatedly caching and recovering weak odor seeds exhibited greater olfactory ability and spatial memory, as indicated by alterations in the protein profiles of the olfactory bulbs and hippocampus. The upregulation of proteins closely related to neural connections between the olfactory bulb and hippocampus is highly responsible for improved olfactory function and spatial memory. Our study provides new insights into how scatter-hoarding rodents manage and respond to cached seeds differing in odor intensity from a neurobiological perspective, which is of significant importance for better understanding the parallel evolution of the olfactory and hippocampal systems.
期刊介绍:
Behavioural Brain Research is an international, interdisciplinary journal dedicated to the publication of articles in the field of behavioural neuroscience, broadly defined. Contributions from the entire range of disciplines that comprise the neurosciences, behavioural sciences or cognitive sciences are appropriate, as long as the goal is to delineate the neural mechanisms underlying behaviour. Thus, studies may range from neurophysiological, neuroanatomical, neurochemical or neuropharmacological analysis of brain-behaviour relations, including the use of molecular genetic or behavioural genetic approaches, to studies that involve the use of brain imaging techniques, to neuroethological studies. Reports of original research, of major methodological advances, or of novel conceptual approaches are all encouraged. The journal will also consider critical reviews on selected topics.