Transitioning ecosystems: how will permafrost cryophiles respond to a changing climate?

Permafrost harbours a diversity of cryophilic microorganisms that can be metabolically active at sub-zero temperatures and likely play a role in global carbon cycling. This forum article explores possible impacts of permafrost warming on cold-adapted microbiota, highlights underexplored areas of research, and suggests future short and long-term research foci.