利用特征消除和超参数优化通过心脏排出图监测胎儿的实用方法

IF 3.9 2区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Fırat Hardalaç, Haad Akmal, Kubilay Ayturan, U Rajendra Acharya, Ru-San Tan
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引用次数: 0

摘要

胎儿心动图(CTG)用于评估胎儿出生时或产前三个月的健康状况。它可同时检测母体子宫收缩(UC)和胎儿心率(FHR)。胎儿窘迫可能需要治疗干预,可通过基线 FHR 及其对子宫收缩的反应进行诊断。本研究利用 CTG,提出了一种基于特征缩减和超参数优化的实用机器学习策略,用于对各种胎儿状态(正常、可疑、病理)进行分类。这一策略的应用可作为管理妊娠的决策支持工具。在 2126 个 CTG 记录的公共数据集上,使用各种标准 CTG 数据集专用的相关分类器对模型进行了评估。建议的方法提高了分类器的准确性。使用随机森林(最佳分类器)时,模型准确率提高到 97.20%。实际上,该模型能够正确预测数据集中 100% 的病理病例和 98.8% 的正常病例。我们还在另一个包含 552 个 CTG 信号的公共 CTG 数据集上实施了所提出的模型,结果准确率达到 97.34%。如果与远程医疗相结合,该模型还可用于高危妊娠的远程 "在家 "胎儿监护。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Pragmatic Approach to Fetal Monitoring via Cardiotocography Using Feature Elimination and Hyperparameter Optimization.

Cardiotocography (CTG) is used to assess the health of the fetus during birth or antenatally in the third trimester. It concurrently detects the maternal uterine contractions (UC) and fetal heart rate (FHR). Fetal distress, which may require therapeutic intervention, can be diagnosed using baseline FHR and its reaction to uterine contractions. Using CTG, a pragmatic machine learning strategy based on feature reduction and hyperparameter optimization was suggested in this study to classify the various fetal states (Normal, Suspect, Pathological). An application of this strategy can be a decision support tool to manage pregnancies. On a public dataset of 2126 CTG recordings, the model was assessed using various standard CTG dataset specific and relevant classifiers. The classifiers' accuracy was improved by the proposed method. The model accuracy was increased to 97.20% while using Random Forest (best classifier). Practically speaking, the model was able to correctly predict 100% of all pathological cases and 98.8% of all normal cases in the dataset. The proposed model was also implemented on another public CTG dataset having 552 CTG signals, resulting in a 97.34% accuracy. If integrated with telemedicine, this proposed model could also be used for long-distance "stay at home" fetal monitoring in high-risk pregnancies.

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来源期刊
Interdisciplinary Sciences: Computational Life Sciences
Interdisciplinary Sciences: Computational Life Sciences MATHEMATICAL & COMPUTATIONAL BIOLOGY-
CiteScore
8.60
自引率
4.20%
发文量
55
期刊介绍: Interdisciplinary Sciences--Computational Life Sciences aims to cover the most recent and outstanding developments in interdisciplinary areas of sciences, especially focusing on computational life sciences, an area that is enjoying rapid development at the forefront of scientific research and technology. The journal publishes original papers of significant general interest covering recent research and developments. Articles will be published rapidly by taking full advantage of internet technology for online submission and peer-reviewing of manuscripts, and then by publishing OnlineFirstTM through SpringerLink even before the issue is built or sent to the printer. The editorial board consists of many leading scientists with international reputation, among others, Luc Montagnier (UNESCO, France), Dennis Salahub (University of Calgary, Canada), Weitao Yang (Duke University, USA). Prof. Dongqing Wei at the Shanghai Jiatong University is appointed as the editor-in-chief; he made important contributions in bioinformatics and computational physics and is best known for his ground-breaking works on the theory of ferroelectric liquids. With the help from a team of associate editors and the editorial board, an international journal with sound reputation shall be created.
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