Giacomo Emanuele Maria Rizzo, Mario Traina, Dario Ligresti, Lucio Carrozza, Gabriele Rancatore, Rosa Liotta, Alessandro Bertani, Ilaria Tarantino
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引用次数: 0
摘要
背景和目的:肺部肿块是内窥镜超声(EUS)组织采集领域的诊断难题,尤其是通过经食道EUS-FNB(细针活检)。我们的研究评估了肺部病变 EUS-FNB 的可行性、诊断性能和安全性:方法:53 名患者被纳入前瞻性登记。所有 EUS 手术均由经验丰富的内镜医师进行。结果:患者平均年龄(70±10.0)岁,平均年龄(70±10.0)岁,平均年龄(70±10.0)岁,平均年龄(70±10.0)岁,平均年龄(70±10.0)岁:平均年龄(70±10.4)岁,男性占 71.7%。平均病灶大小为(52.4±23.3)毫米,患者多为单发病灶(86.8%)。大多数患者确诊时已是晚期(IV 期,41.82%),最常见的肺癌是非小细胞肺癌(69.4%)。诊断充分率为92.86%,诊断准确率为87.5%。3例手术出现不良反应:结论:经食管 EUS-FNB 是对 EUS 可触及的肺部肿块进行组织取样的一种可行且安全的诊断方法。
Endoscopic Ultrasound-guided Transesophageal Fine-Needle Biopsy of Lung Masses: Diagnostic Performance and Safety.
Background and aims: Pulmonary masses are a diagnostic challenge in the field of endoscopic ultrasound(EUS) tissue acquisition, especially through transesophageal EUS-FNB(fine needle biopsy). Our study evaluated the feasibility, diagnostic performance, and safety of EUS-FNB of pulmonary lesions.
Methods: Fifty-three patients were enrolled in a prospective registry. All of the EUS procedures were performed by experienced endosonographers. Outcomes were specimen adequacy, diagnostic accuracy, diagnostic sensibility, diagnostic specificity, and safety.
Results: The mean age was 70±10.4, and 71.7% were male. The mean lesion size was 52.4±23.3 mm, and patients had mostly a single lesion(86.8%). Most of the patients had advanced stage at diagnosis(stage IV, 41.82%), and the most common lung cancer was non-small cell lung carcinoma(69.4%). Diagnostic adequacy rate was 92.86%, and diagnostic accuracy was 87.5%. Adverse events were reported in 3 procedures.
Conclusions: Transesophageal EUS-FNB is a feasible and safe diagnostic method of tissue sampling for lung masses reachable by EUS.
期刊介绍:
Gastrointestinal Endoscopy is a journal publishing original, peer-reviewed articles on endoscopic procedures for studying, diagnosing, and treating digestive diseases. It covers outcomes research, prospective studies, and controlled trials of new endoscopic instruments and treatment methods. The online features include full-text articles, video and audio clips, and MEDLINE links. The journal serves as an international forum for the latest developments in the specialty, offering challenging reports from authorities worldwide. It also publishes abstracts of significant articles from other clinical publications, accompanied by expert commentaries.