药房 3D 打印。

IF 8.2 2区 医学 Q1 ENGINEERING, BIOMEDICAL
Jessica Cheng, Edwin Tan, Lifeng Kang
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引用次数: 0

摘要

"一刀切 "的用药方法的一大局限是缺乏对特殊人群的考虑。3D 打印技术彻底改变了制药和药学实践的面貌,在按需生产定制药物方面发挥了不可或缺的作用。与传统制药工艺相比,3D 打印技术在生产具有独特药物释放机制的定制剂型方面具有重大优势。此外,该技术还能在单一配方中结合多种药物,解决用药负担的关键问题。近年来,3D 打印技术在临床应用和大规模制药方面的发展大幅增加。本综述重点介绍基于挤压的 3D 打印技术,特别是半固态挤压、熔融沉积建模和直接粉末挤压,这些技术目前在制药实践中最常被研究。本文概述了每种技术的概念,并举例说明了当前和潜在的应用。接下来,讨论了 3D 打印机市场的最新进展和药剂师的看法。最后,重点介绍了药学 3D 打印技术的优势、挑战和前景,强调了该技术在改变该领域未来方面的重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pharmacy 3D printing.

A significant limitation of the "one size fits all" medication approach is the lack of consideration for special population groups. 3D printing technology has revolutionised the landscape of pharmaceuticals and pharmacy practice, playing an integral role in enabling on-demand production of customised medication. Compared to traditional pharmaceutical processes, 3D printing has major advantages in producing tailored dosage forms with unique drug release mechanisms. Moreover, this technology has enabled the combination of multiple drugs in a single formulation addressing key issues of medication burden. Development of 3D printing in clinical applications and large-scale pharmaceutical manufacturing has substantially increased in recent years. This review focuses on the emergence of extrusion-based 3D printing, particularly semi solid extrusion, fused deposition modelling and direct powder extrusion, which are currently the most commonly studied in pharmacy practice. The concept of each technique is summarised, with examples of current and potential applications. Next, recent advancements in the 3D printer market and pharmacist perceptions are discussed. Finally, the benefits, challenges and prospects of pharmacy 3D printing technology are highlighted, emphasising its significance in changing the future of this field.

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来源期刊
Biofabrication
Biofabrication ENGINEERING, BIOMEDICAL-MATERIALS SCIENCE, BIOMATERIALS
CiteScore
17.40
自引率
3.30%
发文量
118
审稿时长
2 months
期刊介绍: Biofabrication is dedicated to advancing cutting-edge research on the utilization of cells, proteins, biological materials, and biomaterials as fundamental components for the construction of biological systems and/or therapeutic products. Additionally, it proudly serves as the official journal of the International Society for Biofabrication (ISBF).
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