Johanna Luitjens, Katharina Ziegeler, Daehyun Yoon, Felix Gassert, Rupsa Bhattacharjee, Rawee Manatrakul, Chotigar Ngarmsrikam, Amy Becker, Yang Yang, Gabby B Joseph, Pan Su, Pedro Itriago-Leon, Sharmila Majumdar, Thomas M Link
{"title":"利用新一代低场磁共振成像改进金属抑制:生物模型可行性研究。","authors":"Johanna Luitjens, Katharina Ziegeler, Daehyun Yoon, Felix Gassert, Rupsa Bhattacharjee, Rawee Manatrakul, Chotigar Ngarmsrikam, Amy Becker, Yang Yang, Gabby B Joseph, Pan Su, Pedro Itriago-Leon, Sharmila Majumdar, Thomas M Link","doi":"10.1007/s00256-024-04809-x","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Novel 0.55 MRI scanners have the potential to reduce metal artifacts around orthopedic implants. The purpose of this study was to compare metal artifact size and depiction of anatomy between 0.55 T and 3.0 T MRI in a biophantom.</p><p><strong>Materials and methods: </strong>Steel and titanium screws were implanted in 12 porcine knee specimens and imaging at 0.55 T and 3 T MRI was performed using the following sequences: turbo spin-echo (TSE), TSE with view angle tilting (VAT), and slice encoding for metal artifact correction (SEMAC) with proton-density (PD) and T2-weighted short-tau inversion-recovery (T2w-STIR) contrasts. Artifacts were measured, and visualization of anatomy (cartilage, bone, growth plates, cruciate ligaments) was assessed and compared between groups.</p><p><strong>Results: </strong>Metal artifacts were significantly smaller at 0.55 T. The smallest artifact sizes were achieved with SEMAC at 0.55 T for both PD and T2w-STIR sequences; corresponding relative size reductions vs. 3.0 T were 78.7% and 79.4% (stainless steel) and 45.3% and 1.4% (titanium). Depiction of anatomical structures was superior at 0.55 T.</p><p><strong>Conclusion: </strong>Substantial reduction of artifact size resulting in superior depiction of anatomical structures is possible on novel 0.55 T MRI systems. Further clinical studies are required to elucidate patient-relevant advantages.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Improved metal suppression using new generation low-field MRI: a biophantom feasibility study.\",\"authors\":\"Johanna Luitjens, Katharina Ziegeler, Daehyun Yoon, Felix Gassert, Rupsa Bhattacharjee, Rawee Manatrakul, Chotigar Ngarmsrikam, Amy Becker, Yang Yang, Gabby B Joseph, Pan Su, Pedro Itriago-Leon, Sharmila Majumdar, Thomas M Link\",\"doi\":\"10.1007/s00256-024-04809-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Novel 0.55 MRI scanners have the potential to reduce metal artifacts around orthopedic implants. The purpose of this study was to compare metal artifact size and depiction of anatomy between 0.55 T and 3.0 T MRI in a biophantom.</p><p><strong>Materials and methods: </strong>Steel and titanium screws were implanted in 12 porcine knee specimens and imaging at 0.55 T and 3 T MRI was performed using the following sequences: turbo spin-echo (TSE), TSE with view angle tilting (VAT), and slice encoding for metal artifact correction (SEMAC) with proton-density (PD) and T2-weighted short-tau inversion-recovery (T2w-STIR) contrasts. Artifacts were measured, and visualization of anatomy (cartilage, bone, growth plates, cruciate ligaments) was assessed and compared between groups.</p><p><strong>Results: </strong>Metal artifacts were significantly smaller at 0.55 T. The smallest artifact sizes were achieved with SEMAC at 0.55 T for both PD and T2w-STIR sequences; corresponding relative size reductions vs. 3.0 T were 78.7% and 79.4% (stainless steel) and 45.3% and 1.4% (titanium). Depiction of anatomical structures was superior at 0.55 T.</p><p><strong>Conclusion: </strong>Substantial reduction of artifact size resulting in superior depiction of anatomical structures is possible on novel 0.55 T MRI systems. Further clinical studies are required to elucidate patient-relevant advantages.</p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00256-024-04809-x\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00256-024-04809-x","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
目的:新型 0.55 MRI 扫描仪有可能减少骨科植入物周围的金属伪影。本研究的目的是在生物模型中比较 0.55 T 和 3.0 T MRI 的金属伪影大小和解剖描绘:在 12 个猪膝关节标本中植入钢和钛螺钉,并使用以下序列在 0.55 T 和 3 T MRI 上进行成像:涡轮自旋回波 (TSE)、带视角倾斜 (VAT) 的 TSE、带质子密度 (PD) 和 T2 加权短陶反转恢复 (T2w-STIR) 对比的金属伪影校正切片编码 (SEMAC)。测量伪影,评估解剖结构(软骨、骨、生长板、十字韧带)的可视化情况,并进行组间比较:PD和T2w-STIR序列的金属伪影在0.55 T时明显较小;与3.0 T相比,相应的相对尺寸减少率分别为78.7%和79.4%(不锈钢)以及45.3%和1.4%(钛)。解剖结构的描绘在 0.55 T 时更为出色:结论:新型 0.55 T 磁共振成像系统可大幅减少伪影尺寸,从而更好地描绘解剖结构。需要进一步的临床研究来阐明与患者相关的优势。
Improved metal suppression using new generation low-field MRI: a biophantom feasibility study.
Objective: Novel 0.55 MRI scanners have the potential to reduce metal artifacts around orthopedic implants. The purpose of this study was to compare metal artifact size and depiction of anatomy between 0.55 T and 3.0 T MRI in a biophantom.
Materials and methods: Steel and titanium screws were implanted in 12 porcine knee specimens and imaging at 0.55 T and 3 T MRI was performed using the following sequences: turbo spin-echo (TSE), TSE with view angle tilting (VAT), and slice encoding for metal artifact correction (SEMAC) with proton-density (PD) and T2-weighted short-tau inversion-recovery (T2w-STIR) contrasts. Artifacts were measured, and visualization of anatomy (cartilage, bone, growth plates, cruciate ligaments) was assessed and compared between groups.
Results: Metal artifacts were significantly smaller at 0.55 T. The smallest artifact sizes were achieved with SEMAC at 0.55 T for both PD and T2w-STIR sequences; corresponding relative size reductions vs. 3.0 T were 78.7% and 79.4% (stainless steel) and 45.3% and 1.4% (titanium). Depiction of anatomical structures was superior at 0.55 T.
Conclusion: Substantial reduction of artifact size resulting in superior depiction of anatomical structures is possible on novel 0.55 T MRI systems. Further clinical studies are required to elucidate patient-relevant advantages.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.