利用脑体交流了解癌症。

IF 7.5 1区生物学 Q1 CELL BIOLOGY

Genes & development Pub Date : 2024-10-16 DOI:10.1101/gad.352292.124

Erica K Sloan

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引用次数: 0

摘要

体内出现的实体瘤会与神经元相互作用，从而影响癌症的进展和治疗反应。在此，我们将讨论该领域的关键问题，包括确定肿瘤与神经回路之间相互作用的性质，以及确定神经信号如何塑造肿瘤微环境。这些信息将使我们能够以神经信号为最佳靶点，改善癌症患者的治疗效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Harnessing brain-body communication to understand cancer.

Solid tumors that arise in the body interact with neurons, which influences cancer progression and treatment response. Here, we discuss key questions in the field, including defining the nature of interactions between tumors and neural circuits and defining how neural signals shape the tumor microenvironment. This information will allow us to optimally target neural signaling to improve outcomes for cancer patients.

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来源期刊

Genes & development 生物-发育生物学

CiteScore

17.50

自引率

1.90%

发文量

审稿时长

3-6 weeks

期刊介绍： Genes & Development is a research journal published in association with The Genetics Society. It publishes high-quality research papers in the areas of molecular biology, molecular genetics, and related fields. The journal features various research formats including Research papers, short Research Communications, and Resource/Methodology papers. Genes & Development has gained recognition and is considered as one of the Top Five Research Journals in the field of Molecular Biology and Genetics. It has an impressive Impact Factor of 12.89. The journal is ranked #2 among Developmental Biology research journals, #5 in Genetics and Heredity, and is among the Top 20 in Cell Biology (according to ISI Journal Citation Reports®, 2021).