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引用次数: 0
摘要
背景:目前,耳部瘢痕疙瘩术后治疗的最佳放疗剂量还存在争议:作者比较了手术切除后9.5Gy和10Gy单次电子束放疗的疗效,并评估了放疗时间对疗效的影响:研究对象为2021年5月至2024年6月期间接受手术切除和术后电子束放疗的耳廓瘢痕患者。根据放射剂量(9.5 VS 10)和时间(术后 8 小时内 VS 24 小时内)将患者分为几组。同时还比较了复发率和并发症:研究包括 182 名患者(21 名男性和 161 名女性)。总复发率为 3.3%(6/182)。10-Gy组的复发率明显低于9.5-Gy组(0.81% vs 8.47%; p = .014)。放疗时间对复发率无明显影响(2.59% vs 3.80%,P = 1)。并发症无明显差异:结论:术后单次剂量为10 Gy是预防耳廓瘢痕复发最有效的低剂量单次点阵电子束放疗。一旦在术后24小时内给药,放疗时间对治疗效果没有明显影响。
A Comparative Analysis of Postoperative Single Fraction of 9.5 Gy Versus 10 Gy for Ear Keloids.
Background: The optimal radiotherapy doses for postoperative treatment of ear keloids are currently a topic of debate.
Objective: The authors compared the efficacy of 9.5-Gy and 10-Gy single-fraction electron beam radiation therapy after surgical excision and evaluated the impact of radiation timing on outcomes.
Materials and methods: This study was conducted on patients with ear keloid who underwent surgical excision and postoperative electron beam radiotherapy between May 2021 and June 2024. Patients were divided into groups based on radiation dose (9.5 vs 10) and timing (within 8 hours vs 24 hours postoperatively). Recurrence rates and complications were also compared.
Results: The study included 182 patients (21 men and 161 women). The overall recurrence rate was 3.3% (6/182). The 10-Gy group had a significantly lower recurrence rate than the 9.5-Gy group (0.81% vs 8.47%; p = .014). Radiation timing did not significantly influence recurrence rates (2.59% vs 3.80%, p = 1). Complications were not significantly different.
Conclusion: A postoperative single dose of 10 Gy is the most effective low-dose single fractional electron beam radiotherapy for preventing ear keloid recurrence. Once administered within 24 hours after surgery, the timing of radiotherapy has no significant impact on treatment outcomes.
期刊介绍:
Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including:
-Ambulatory phlebectomy-
Blepharoplasty-
Body contouring-
Chemical peels-
Cryosurgery-
Curettage and desiccation-
Dermabrasion-
Excision and closure-
Flap Surgery-
Grafting-
Hair restoration surgery-
Injectable neuromodulators-
Laser surgery-
Liposuction-
Microdermabrasion-
Microlipoinjection-
Micropigmentation-
Mohs micrographic surgery-
Nail surgery-
Phlebology-
Sclerotherapy-
Skin cancer surgery-
Skin resurfacing-
Soft-tissue fillers.
Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.