一种多态蝾螈生殖发育和基因表达的季节异构性

IF 2 3区 生物学 Q2 ANATOMY & MORPHOLOGY
Madison A Herrboldt, Claire N C Wright, Ronald M Bonett
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引用次数: 0

摘要

背景:生命周期进化包括生态过渡以及体细胞和生殖细胞发育时间的变化(异时性)。然而,异时性变化可能具有组织特异性,最终导致性状的差异多样化。蝾螈表现出不同的生命周期多态性,既有从水生到陆生的变态(双相),也有水生幼体特征保留到成年的多态性(拟态)。在这项研究中,我们利用基因表达和组织学评估了生命周期进化如何影响多态蝾螈雄性的时间繁殖模式:结果:我们发现,异型性改变了雄性激素信号在全身皮肤中的分布,这与季节性生殖腺发育和信息素基因表达的显著差异有关。在睾丸中,雄激素受体(ar)的表达在不同形态或不同季节没有显著差异。我们发现精子发生的起始时间存在明显差异,但到了繁殖高峰期,睾丸的组织学和基因表达都是一样的:本研究提供了一个例子,说明组织特异性 ar 基因表达的季节性异时性变化如何对各组织的季节性发育和表达模式产生不同影响,从而为生殖性状的差异多样化提供了一种潜在机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seasonal heterochrony of reproductive development and gene expression in a polymorphic salamander.

Background: Life cycle evolution includes ecological transitions and shifts in the timing of somatic and reproductive development (heterochrony). However, heterochronic changes can be tissue-specific, ultimately leading to the differential diversification of traits. Salamanders exhibit alternative life cycle polymorphisms involving either an aquatic to terrestrial metamorphosis (biphasic) or retention of aquatic larval traits into adulthood (paedomorphic). In this study, we used gene expression and histology to evaluate how life cycle evolution impacts temporal reproductive patterns in males of a polymorphic salamander.

Results: We found that heterochrony shifts the distribution of androgen signaling in the integument, which is correlated with significant differences in seasonal reproductive gland development and pheromone gene expression. In the testes, androgen receptor (ar) expression does not significantly vary between morphs or across seasons. We found significant differences in the onset of spermatogenesis, but by peak breeding season the testes were the same with respect to both histology and gene expression.

Conclusion: This study provides an example of how seasonal heterochronic shifts in tissue-specific ar gene expression can disparately impact seasonal development and expression patterns across tissues, providing a potential mechanism for differential diversification of reproductive traits.

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来源期刊
Developmental Dynamics
Developmental Dynamics 生物-发育生物学
CiteScore
5.10
自引率
8.00%
发文量
116
审稿时长
3-8 weeks
期刊介绍: Developmental Dynamics, is an official publication of the American Association for Anatomy. This peer reviewed journal provides an international forum for publishing novel discoveries, using any model system, that advances our understanding of development, morphology, form and function, evolution, disease, stem cells, repair and regeneration.
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