两心相印：关于 RAS 二聚体的争论仍在继续。

IF 3.5 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

ACS Chemical Biology Pub Date : 2024-11-01 Epub Date: 2024-10-01 DOI:10.1016/j.tibs.2024.09.005

Andrew G Stephen

引用次数: 0

摘要

Yun 等人最近的一篇报告介绍了利用完整质谱检测 RAS 二聚体的方法，并研究了膜脂质、核苷酸状态和结合伙伴在二聚体形成过程中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Two hearts beat as one: the debate over RAS dimers continues.

A recent report by Yun et al. describes the detection of RAS dimers using intact mass spectrometry and investigates the role that membrane lipids, nucleotide state, and binding partners have in their formation.

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来源期刊

ACS Chemical Biology 生物-生化与分子生物学

CiteScore

7.50

自引率

5.00%

发文量

353

审稿时长

3.3 months

期刊介绍： ACS Chemical Biology provides an international forum for the rapid communication of research that broadly embraces the interface between chemistry and biology. The journal also serves as a forum to facilitate the communication between biologists and chemists that will translate into new research opportunities and discoveries. Results will be published in which molecular reasoning has been used to probe questions through in vitro investigations, cell biological methods, or organismic studies. We welcome mechanistic studies on proteins, nucleic acids, sugars, lipids, and nonbiological polymers. The journal serves a large scientific community, exploring cellular function from both chemical and biological perspectives. It is understood that submitted work is based upon original results and has not been published previously.