[骨质疏松症--定义、风险评估、诊断、预防和治疗(2024 年更新):奥地利骨与矿物质研究学会指南]。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-10-02 DOI:10.1007/s00508-024-02441-2
Hans Peter Dimai, Christian Muschitz, Karin Amrein, Rosemarie Bauer, Daniel Cejka, Rudolf Wolfgang Gasser, Reinhard Gruber, Judith Haschka, Timothy Hasenöhrl, Franz Kainberger, Katharina Kerschan-Schindl, Roland Kocijan, Jürgen König, Norbert Kroißenbrunner, Ulrike Kuchler, Christine Oberforcher, Johannes Ott, Georg Pfeiler, Peter Pietschmann, Paul Puchwein, Alexander Schmidt-Ilsinger, Ralf Harun Zwick, Astrid Fahrleitner-Pammer
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引用次数: 0

摘要

背景:奥地利是全球骨质疏松性骨折发病率和流行率最高的国家之一。骨质疏松症的预防和管理指南于 2010 年在当时的奥地利社会保障机构联合会主持下首次发布,并于 2017 年更新。奥地利骨与矿物质研究学会目前全面更新的指南面向所有专业的医生以及奥地利医疗保健系统的决策者和机构。这些指南旨在加强和提高奥地利骨质疏松症和骨质疏松性骨折患者的医疗质量:这些以证据为基础的建议是在考虑了随机对照试验、系统综述和荟萃分析以及 2023 年 6 月 1 日之前发布的欧洲和国际参考指南后编制而成的。所使用的建议分级("有条件 "和 "强")基于证据的强度。所使用的证据等级是 SIGN(1++至3)与 NOGG 标准(Ia 至 IV)的相互转换:该指南包括与骨质疏松症和骨质疏松性骨折相关的所有方面,如继发性原因、预防、诊断、使用 FRAX® 估算 10 年骨折风险、确定基于 FRAX® 的奥地利特定干预阈值、基于药物和非基于药物的治疗方案以及治疗监测。针对诊室环境以及奥地利医疗保健系统的决策者和机构的建议考虑了结构化医疗模式和骨质疏松症筛查方案:该指南为骨质疏松症的治疗提供了全面、循证的信息和指导。预计奥地利各级医疗保健系统对这种临床症状患者的医疗保健质量将得到大幅提高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Osteoporosis-Definition, risk assessment, diagnosis, prevention and treatment (update 2024) : Guidelines of the Austrian Society for Bone and Mineral Research].

Background: Austria is among the countries with the highest incidence and prevalence of osteoporotic fractures worldwide. Guidelines for the prevention and management of osteoporosis were first published in 2010 under the auspices of the then Federation of Austrian Social Security Institutions and updated in 2017. The present comprehensively updated guidelines of the Austrian Society for Bone and Mineral Research are aimed at physicians of all specialties as well as decision makers and institutions in the Austrian healthcare system. The aim of these guidelines is to strengthen and improve the quality of medical care of patients with osteoporosis and osteoporotic fractures in Austria.

Methods: These evidence-based recommendations were compiled taking randomized controlled trials, systematic reviews and meta-analyses as well as European and international reference guidelines published before 1 June 2023 into consideration. The grading of recommendations used ("conditional" and "strong") are based on the strength of the evidence. The evidence levels used mutual conversions of SIGN (1++ to 3) to NOGG criteria (Ia to IV).

Results: The guidelines include all aspects associated with osteoporosis and osteoporotic fractures, such as secondary causes, prevention, diagnosis, estimation of the 10-year fracture risk using FRAX®, determination of Austria-specific FRAX®-based intervention thresholds, drug-based and non-drug-based treatment options and treatment monitoring. Recommendations for the office-based setting and decision makers and institutions in the Austrian healthcare system consider structured care models and options for osteoporosis-specific screening.

Conclusion: The guidelines present comprehensive, evidence-based information and instructions for the treatment of osteoporosis. It is expected that the quality of medical care for patients with this clinical picture will be substantially improved at all levels of the Austrian healthcare system.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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