整合68Ga-Pentixafor和68Ga-FAPI-04 PET/MR用于诊断肾上腺醛固酮生成腺瘤和附属脾结节。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-02 DOI:10.1097/RLU.0000000000005475

Jie Ding, Weilun Wang, Xing Chen, Zhiwen You, Jun Zhao

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引用次数: 0

摘要

摘要：一名患有原发性醛固酮增多症的 57 岁男子在左肾上腺、胰尾和脾区出现多个结节。左肾上腺结节显示 68Ga-pentixafor 摄取阳性，68Ga-FAPI-04 摄取阴性，提示为产生醛固酮的肾上腺腺瘤。胰腺尾部的结节显示出高 68Ga-pentixafor 摄取和低 68Ga-FAPI-04 摄取，与脾脏区域的结节相似，表明为脾脏附属结节。术后病理证实了肾上腺皮质腺瘤和胰腺附属脾结节。该病例强调了 68Ga-pentixafor 和 68Ga-FAPI-04 PET/MR 在诊断复杂的肾上腺和胰腺病变中的互补作用。

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Integrated 68 Ga-Pentixafor and 68 Ga-FAPI-04 PET/MR for Diagnosing Adrenal Aldosterone-Producing Adenoma and Accessory Splenic Nodules.

Abstract: A 57-year-old man with primary aldosteronism exhibited multiple nodules in the left adrenal, pancreatic tail, and splenic region. The left adrenal nodule showed positive 68 Ga-pentixafor and negative 68 Ga-FAPI-04 uptake, suggesting an aldosterone-producing adrenal adenoma. The nodule in the pancreatic tail exhibited high 68 Ga-pentixafor and low 68 Ga-FAPI-04 uptake, similarity with the nodule in splenic region, indicating accessory splenic nodule. Postoperative pathology confirmed an adrenal cortical adenoma and an accessory splenic nodule in the pancreas. This case underscores the complementary role of 68 Ga-pentixafor and 68 Ga-FAPI-04 PET/MR in diagnosing complex adrenal and pancreatic pathologies.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.