通过胸腔镜肺活检确诊的原发性肺结节外 NK/T 细胞淋巴瘤：病例报告

IF 0.8 Q4 RESPIRATORY SYSTEM

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI:10.1016/j.rmcr.2024.102127

Michihiko Tanaka , Yasushi Horimasu , Kazuma Kawamoto , Taro Edahiro , Kakuhiro Yamaguchi , Shinjiro Sakamoto , Takeshi Masuda , Taku Nakashima , Hiroshi Iwamoto , Kazunori Fujitaka , Hironobu Hamada , Tatsuo Ichinohe , Noboru Hattori

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引用次数: 0

摘要

一名 63 岁的日本女性因发烧就诊。计算机断层扫描显示双肺多发结节。医生使用皮质类固醇和抗生素治疗疑似机化性肺炎和细菌性肺炎，结果病情无好转，呼吸衰竭加重。手术肺活检发现 CD3、CD56、颗粒酶 B 和 EBV 编码 RNA-ISH 阳性的非典型淋巴细胞浸润。她被诊断为原发性肺结节外 NK/T 细胞淋巴瘤（ENKL），确诊两个月后死亡，化疗仅暂时有效。我们应考虑到ENKL的可能性，在对疑似肺炎进行经验性治疗无效时，应及时进行适当的活检以早期诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Primary pulmonary extranodal NK/T-cell lymphoma diagnosed by thoracoscopic lung biopsy: A case report

A 63-year-old Japanese female presented with fever. Computed tomography showed multiple nodules in both lungs. Corticosteroids and antibiotics were administered to treat suspected organizing and bacterial pneumonia, resulting in no improvement and respiratory failure worsened. Surgical lung biopsy revealed infiltration of CD3, CD56, Granzyme B, and EBV-encoded RNA-ISH-positive atypical lymphocytes. She was diagnosed with primary pulmonary extranodal NK/T-cell lymphoma (ENKL) and died two months after diagnosis with only a temporary effectiveness of chemotherapy. We should consider the possibility of ENKL and perform prompt and appropriate biopsy for early diagnosis in cases where empiric therapy is ineffective for suspected pneumonia.

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来源期刊

Respiratory Medicine Case Reports RESPIRATORY SYSTEM-

CiteScore

2.10

自引率

0.00%

发文量

213

审稿时长

87 days