Tomasz Szostek , Dagmara Otto-Ślusarczyk , Piotr Roszkowski , Marta Struga , Daniel Szulczyk
{"title":"探索（2-亚氨基-4-氧代-1,3-噻唑烷-5-基）乙酸衍生物的生物活性潜力：综述","authors":"Tomasz Szostek , Dagmara Otto-Ślusarczyk , Piotr Roszkowski , Marta Struga , Daniel Szulczyk","doi":"10.1016/j.rechem.2024.101828","DOIUrl":null,"url":null,"abstract":"<div><div>Thiazolidinone is a scaffold known for its diverse biological activities, drawing the interest of researchers seeking to explore its potential. Numerous libraries of molecules with diverse structures and properties can be created based on this scaffold. We propose the extraction of compounds with a defined central skeleton, resulting from a repeatable methodology of synthesis, to analyze the biological properties of a heterogeneous set of molecules. This review offers a comprehensive overview of recent research, focusing on a homogeneous group of (2-imino-4-oxo-1,3-thiazolidin-5-yl)acetic acid derivatives. It highlights the most promising compounds that have emerged from recent studies, their molecular targets, and the underlying mechanisms contributing to their biological activity.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"11 ","pages":"Article 101828"},"PeriodicalIF":2.5000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Exploring the bioactive potential of (2-imino-4-oxo-1,3-thiazolidin-5-yl)acetic acid derivatives: A comprehensive review\",\"authors\":\"Tomasz Szostek , Dagmara Otto-Ślusarczyk , Piotr Roszkowski , Marta Struga , Daniel Szulczyk\",\"doi\":\"10.1016/j.rechem.2024.101828\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Thiazolidinone is a scaffold known for its diverse biological activities, drawing the interest of researchers seeking to explore its potential. Numerous libraries of molecules with diverse structures and properties can be created based on this scaffold. We propose the extraction of compounds with a defined central skeleton, resulting from a repeatable methodology of synthesis, to analyze the biological properties of a heterogeneous set of molecules. This review offers a comprehensive overview of recent research, focusing on a homogeneous group of (2-imino-4-oxo-1,3-thiazolidin-5-yl)acetic acid derivatives. It highlights the most promising compounds that have emerged from recent studies, their molecular targets, and the underlying mechanisms contributing to their biological activity.</div></div>\",\"PeriodicalId\":420,\"journal\":{\"name\":\"Results in Chemistry\",\"volume\":\"11 \",\"pages\":\"Article 101828\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Results in Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211715624005241\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Results in Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211715624005241","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Exploring the bioactive potential of (2-imino-4-oxo-1,3-thiazolidin-5-yl)acetic acid derivatives: A comprehensive review
Thiazolidinone is a scaffold known for its diverse biological activities, drawing the interest of researchers seeking to explore its potential. Numerous libraries of molecules with diverse structures and properties can be created based on this scaffold. We propose the extraction of compounds with a defined central skeleton, resulting from a repeatable methodology of synthesis, to analyze the biological properties of a heterogeneous set of molecules. This review offers a comprehensive overview of recent research, focusing on a homogeneous group of (2-imino-4-oxo-1,3-thiazolidin-5-yl)acetic acid derivatives. It highlights the most promising compounds that have emerged from recent studies, their molecular targets, and the underlying mechanisms contributing to their biological activity.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
