Vitabiotic:治疗糖尿病足的另一种方法。

IF 3.8 3区 医学 Q2 CELL BIOLOGY
Wound Repair and Regeneration Pub Date : 2024-11-01 Epub Date: 2024-09-25 DOI:10.1111/wrr.13222
Hüseyin A Erdem, Nazlıhan Yalçın, Arda Kaya, Meltem Taşbakan
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引用次数: 0

摘要

糖尿病足溃疡和感染是一种并发症,可导致严重的发病率,如需要截肢,尤其是在糖尿病未得到控制的情况下,从而严重影响生活质量。虽然伤口护理和抗生素等传统治疗方法有效,但人们对微量营养素(如维生素 C、D、E、锌和镁)在改善治疗效果方面的作用越来越感兴趣。这项研究旨在评估这些微量营养素对糖尿病足感染和截肢需求的影响,为改善总体预后提供见解。研究纳入了 2022 年 4 月 1 日至 2023 年 1 月 31 日期间在埃格大学医学院附属医院传染科住院并被诊断为糖尿病足感染的患者。病例报告表中记录了患者的社会人口学信息、糖尿病伤口特征、手术史以及微量营养素水平。研究共纳入了 202 名患者。最常见的微量营养素缺乏症是维生素D(69%)、维生素C(64%)和锌(49%)。缺乏维生素 C、维生素 A 和维生素 D 的患者截肢率明显较高(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitabiotic: An alternative approach to diabetic foot.

Diabetic foot ulcers and infections are complications that can result in significant morbidity such as the need for amputations, especially in uncontrolled diabetes, thereby profoundly impacting quality of life. While traditional treatments like wound care and antibiotics are effective, there is growing interest in the role of micronutrients (such as vitamins C, D, E, zinc and magnesium) in improving outcomes. This study aims to evaluate how these micronutrients affect diabetic foot infections and the need for amputation, offering insights to enhance overall prognosis. Patients who were hospitalised with a diagnosis of diabetic foot infection in the Infectious Diseases Department of Ege University Faculty of Medicine Hospital between 1 April 2022, and 31 January 2023 were included in the study. The patients' socio-demographic information, characteristics of diabetic wounds, operation history, as well as their levels of micronutrients recorded on the case report form. A total of 202 patients were included in the study. The most common micronutrient deficiencies were vitamin D (69%), vitamin C (64%) and zinc (49%). The amputation rates were significantly higher in patients with deficiencies vitamin C, vitamin A and vitamin D (p < 0.005). Our research revealed a significant prevalence of vitamin deficiencies among the participants, and we observed a noteworthy correlation between amputation rates and these deficiencies. Although these findings show promise, it is essential to emphasise that micronutrient supplements should not replace traditional treatments but should rather be considered as a warning sign for preventing complications, particularly amputation or extremity loss.

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来源期刊
Wound Repair and Regeneration
Wound Repair and Regeneration 医学-皮肤病学
CiteScore
5.90
自引率
3.40%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Wound Repair and Regeneration provides extensive international coverage of cellular and molecular biology, connective tissue, and biological mediator studies in the field of tissue repair and regeneration and serves a diverse audience of surgeons, plastic surgeons, dermatologists, biochemists, cell biologists, and others. Wound Repair and Regeneration is the official journal of The Wound Healing Society, The European Tissue Repair Society, The Japanese Society for Wound Healing, and The Australian Wound Management Association.
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