[复杂性区域疼痛综合征 12 个月后疗效的前瞻性多中心研究]。

IF 1.1 4区 医学 Q3 ANESTHESIOLOGY
Schmerz Pub Date : 2024-09-28 DOI:10.1007/s00482-024-00837-7
H Hofbauer, A Brinkmann, E Maurer, B Weber, G Hänle, P Steffen
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引用次数: 0

摘要

背景和目的:复杂性区域疼痛综合征(CRPS)可导致严重的疼痛,并在长期内限制患者的功能。指南应有助于优化治疗程序。材料和方法:在一项前瞻性多中心研究中,40 名新发区域性疼痛综合征患者接受了基于指南的治疗:在一项前瞻性多中心研究中,40 名新确诊的 CRPS 患者接受了检查,以确定他们的疼痛和功能限制在 1 年内的变化情况。此外,研究还探讨了诊断时间和侵入性措施是否会影响这些结果参数:所有患者均接受了物理治疗和/或工效治疗,29 例(72.5%)患者接受了糖皮质激素和/或双膦酸盐治疗;13 例(32.5%)患者接受了各种侵入性措施。一年后,患者的疼痛和功能均有明显改善;三分之二的患者表示平均疼痛强度可以忍受。根据 von Korff 残疾积分,1 年后发现有 9 名患者(22.5%)出现严重功能障碍,根据医学评估,分别有 6 名患者(15%)和 3 名患者(7.5%)出现中度或重度功能障碍。根据von Korff评分,早期诊断和相应的早期治疗与疼痛和功能方面更好的结果相关,但与医学评估结果无关。侵入性治疗对疗效参数的影响较小:结论:基于指南的治疗使大多数患者在疼痛和功能方面获得了良好的疗效。早期诊断与更好的疗效相关,因此应尽快将疑似病例转诊到具有相应专业知识的医疗机构。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Prospective, multicenter study of the outcome of complex regional pain syndrome after 12 months].

Background and objectives: Complex regional pain syndrome (CRPS) can lead to severe pain and limited functionality in the long term. Guidelines should help to optimize treatment procedures. It should be investigated which outcome is achieved after 1 year with guideline-based therapy.

Materials and methods: In a prospective multicenter study, 40 patients with newly diagnosed CRPS were examined to determine how their pain and functional limitations changed within 1 year. In addition, it was investigated whether the time of diagnosis and invasive measures influence these outcome parameters.

Results: All patients received physiotherapy and/or ergotherapy, treatment with glucocorticoids and/or bisphosphonates 29 (72.5%); various invasive measures were carried out in 13 (32.5%). After 1 year, both pain and functionality were significantly improved; two-thirds reported a tolerable average pain intensity. Severe functional impairment according to von Korff disability points was found after 1 year in 9 (22.5%), and a moderate or severe impairment according to medical evaluation in 6 (15%) and 3 (7.5%) patients, respectively. Earlier diagnosis and corresponding earlier start of treatment correlated with better outcome in terms of pain and functionality according to von Korff, but not according to medical evaluation. The influence of invasive procedures on the outcome parameters tended to be low.

Conclusion: Guideline-based treatment led to a good outcome in terms of pain and functionality in the majority of patients. Early diagnosis correlated with better outcome, so suspected cases should be referred quickly to a medical facility with appropriate expertise.

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来源期刊
Schmerz
Schmerz 医学-临床神经学
CiteScore
2.00
自引率
20.00%
发文量
64
审稿时长
6-12 weeks
期刊介绍: Der Schmerz is an internationally recognized journal and addresses all scientists, practitioners and psychologists, dealing with the treatment of pain patients or working in pain research. The aim of the journal is to enhance the treatment of pain patients in the long run. Review articles provide an overview on selected topics and offer the reader a summary of current findings from all fields of pain research, pain management and pain symptom management. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.
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