心肾综合征：不断发展的概念和儿科知识差距。

IF 2.6 3区医学 Q1 PEDIATRICS

Pediatric Nephrology Pub Date : 2025-03-01 Epub Date: 2024-09-27 DOI:10.1007/s00467-024-06517-z

Alexander J Kula, Deirdre Bartlett

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引用次数: 0

摘要

心肾综合征（CRS）是指心脏和肾脏同时出现功能障碍。心肾综合征的病理变化是双向的。许多肾病患者会出现心血管并发症。相反，心脏病患者的急性肾损伤和慢性肾病发病率也很高。在过去的 15 年中，我们对 CRS 的认识有了很大的提高，但大多数研究都是在成人群体中进行的。要改善儿童和青少年的心肾功能预后，需要加强跨器官系统的合作和研究。本综述旨在讨论 CRS 的主要特征，并帮助人们了解未来儿科特定研究的机会。

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Cardiorenal syndrome: evolving concepts and pediatric knowledge gaps.

Cardiorenal syndrome (CRS) refers to concomitant dysfunction of both the heart and kidneys. The pathology in CRS is bidirectional. Many individuals with kidney disease will develop cardiovascular complications. Conversely, rates of acute kidney injury and chronic kidney disease are high in cardiac patients. While our understanding of CRS has greatly increased over the past 15 years, most research has occurred in adult populations. Improving cardiorenal outcomes in children and adolescents requires increased collaboration and research that spans organ systems. The purpose of this review is to discuss key features of CRS and help bring to light future opportunities for pediatric-specific research.

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来源期刊

Pediatric Nephrology 医学-泌尿学与肾脏学

CiteScore

4.70

自引率

20.00%

发文量

465

审稿时长

1 months

期刊介绍： International Pediatric Nephrology Association Pediatric Nephrology publishes original clinical research related to acute and chronic diseases that affect renal function, blood pressure, and fluid and electrolyte disorders in children. Studies may involve medical, surgical, nutritional, physiologic, biochemical, genetic, pathologic or immunologic aspects of disease, imaging techniques or consequences of acute or chronic kidney disease. There are 12 issues per year that contain Editorial Commentaries, Reviews, Educational Reviews, Original Articles, Brief Reports, Rapid Communications, Clinical Quizzes, and Letters to the Editors.