特立尼达和多巴哥一个近亲繁殖杂种狗家族中的甲状腺滤泡癌。

IF 1.2 3区农林科学 Q3 VETERINARY SCIENCES

Journal of Veterinary Diagnostic Investigation Pub Date : 2024-11-01 Epub Date: 2024-09-30 DOI:10.1177/10406387241268203

Rod Suepaul, Stacy Rajh, Patricia Pow-Brown, Indira Pargass, Alissa Bally, Lana Gyan, Karelma Frontera-Acevedo

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引用次数: 0

摘要

甲状腺肿瘤发生在许多家畜物种中，但在狗中最为常见，可分为滤泡性和髓质性两种。2012 年至 2016 年期间，我们收到了 4 只患有甲状腺不同程度肿大的狗的组织标本或整个尸体。2公2母均为近亲混血（杂种）犬，年龄在3-4.5岁之间。所有肿瘤均呈分叶状结构，形成滤泡状结构，其中含有不同程度的胶质。在对其中三只狗的肿瘤进行免疫组化时，两只狗的甲状腺球蛋白呈阳性，而所有三只狗的降钙素均呈阴性，这证实了其中两只狗患有滤泡性甲状腺癌。据我们所知，以前还没有相关杂种狗患甲状腺癌的报道。

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Follicular thyroid carcinoma in an inbred family of mongrel dogs in Trinidad & Tobago.

Thyroid tumors occur in many domestic species, but are most common in the dog, in which they are classified as follicular or medullary. During 2012-2016, we received tissue specimens or whole carcasses of 4 dogs with variable enlargement of the thyroid glands. The 2 males and 2 females were of mixed (mongrel) inbreeding, 3-4.5-y-old. All tumors had lobulated architecture forming follicular structures variably containing colloid. On immunohistochemistry of the tumors from 3 of the dogs, 2 were thyroglobulin positive, and all 3 were negative for calcitonin, confirming follicular thyroid carcinoma in 2 of the dogs. Thyroid carcinomas have not been reported previously in related mongrel dogs, to our knowledge.

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来源期刊

Journal of Veterinary Diagnostic Investigation 农林科学-兽医学

CiteScore

3.00

自引率

6.70%

发文量

127

审稿时长

6-16 weeks

期刊介绍： The Journal of Veterinary Diagnostic Investigation (J Vet Diagn Invest) is an international peer-reviewed journal published bimonthly in English by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). JVDI is devoted to all aspects of veterinary laboratory diagnostic science including the major disciplines of anatomic pathology, bacteriology/mycology, clinical pathology, epidemiology, immunology, laboratory information management, molecular biology, parasitology, public health, toxicology, and virology.