Joonbum Seo, José Novo Matos, John S. Munday, Hayley Hunt, David J. Connolly, Virginia Luis Fuentes
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Cats were eligible if they had been diagnosed with HCM and had a repeat echocardiogram ≥1 year later. Clinical and echocardiographic data of the left heart variables were collected.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Thirty-eight cats had SAM at the initial scan. After a median follow-up time of 2.1 years (range: 1.0-5.9), 7 cats had lost SAM (18%) and 5 cats (23%) gained SAM. On follow-up, cats with SAM at the initial scan had a larger left atrium (<i>P</i> = .037), lower left atrial fractional shortening (<i>P</i> = .014), greater LV internal diameter in end-systole (<i>P</i> = .002), and lower LV fractional shortening (<i>P</i> < .001). Four cats with SAM developed congestive heart failure. There were no new cases of congestive heart failure or change in left heart variables in cats without SAM at the initial scan. The gain or loss of SAM was not associated with age or time between scans.</p>\n </section>\n \n <section>\n \n <h3> Conclusions and Clinical Importance</h3>\n \n <p>Similar proportions of cats gained or lost SAM. Cats with SAM at baseline had more evidence of disease progression than cats without SAM.</p>\n </section>\n </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"38 6","pages":"2982-2993"},"PeriodicalIF":2.1000,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.17203","citationCount":"0","resultStr":"{\"title\":\"Longitudinal assessment of systolic anterior motion of the mitral valve in cats with hypertrophic cardiomyopathy\",\"authors\":\"Joonbum Seo, José Novo Matos, John S. Munday, Hayley Hunt, David J. 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引用次数: 0
摘要
背景：肥厚型心肌病 (HCM) 猫二尖瓣收缩期前移 (SAM) 长期丧失的比例尚不清楚：假设/目标：患有 HCM 的猫会长期丧失二尖瓣收缩前运动。SAM的丧失将与年龄增大、扫描间隔延长和左心室（LV）尺寸改变有关：方法：一项回顾性队列研究：方法：来自 2 个转诊中心的回顾性队列研究。被诊断为 HCM 的猫咪在≥1 年后重复超声心动图检查时均符合条件。收集了左心变量的临床和超声心动图数据：结果：38 只猫在初次扫描时患有 SAM。中位随访时间为 2.1 年（范围：1.0-5.9），7 只猫咪失去了 SAM（18%），5 只猫咪获得了 SAM（23%）。随访发现，初次扫描时患有 SAM 的猫左心房较大（P = .037），左心房分数缩短率较低（P = .014），收缩末期左心室内径较大（P = .002），左心室分数缩短率较低（P 结论和临床重要性：获得或丧失 SAM 的猫的比例相似。基线时有 SAM 的猫比没有 SAM 的猫有更多疾病进展的证据。
Longitudinal assessment of systolic anterior motion of the mitral valve in cats with hypertrophic cardiomyopathy
Background
The proportion of cats with hypertrophic cardiomyopathy (HCM) that lose systolic anterior motion of the mitral valve (SAM) in the long term is unknown.
Hypothesis/Objectives
Cats with HCM will lose SAM in the long term. Loss of SAM will be associated with greater age, longer scan-interval, and altered left ventricular (LV) dimensions.
Animals
Sixty unsedated cats with HCM, not receiving beta blockers or pimobendan.
Methods
A retrospective cohort study from 2 referral centers. Cats were eligible if they had been diagnosed with HCM and had a repeat echocardiogram ≥1 year later. Clinical and echocardiographic data of the left heart variables were collected.
Results
Thirty-eight cats had SAM at the initial scan. After a median follow-up time of 2.1 years (range: 1.0-5.9), 7 cats had lost SAM (18%) and 5 cats (23%) gained SAM. On follow-up, cats with SAM at the initial scan had a larger left atrium (P = .037), lower left atrial fractional shortening (P = .014), greater LV internal diameter in end-systole (P = .002), and lower LV fractional shortening (P < .001). Four cats with SAM developed congestive heart failure. There were no new cases of congestive heart failure or change in left heart variables in cats without SAM at the initial scan. The gain or loss of SAM was not associated with age or time between scans.
Conclusions and Clinical Importance
Similar proportions of cats gained or lost SAM. Cats with SAM at baseline had more evidence of disease progression than cats without SAM.
期刊介绍：
The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.
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