用客观营养指标和预测指标评估 COVID-19 住院患者的营养不良情况。

IF 2 4区 医学 Q3 NUTRITION & DIETETICS
Journal of Clinical Biochemistry and Nutrition Pub Date : 2024-09-01 Epub Date: 2024-06-28 DOI:10.3164/jcbn.24-73
Lingmei Zhou, Zhen Ding, Qi Wang, Runjinxing Wu, Kemei Jin
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引用次数: 0

摘要

有关 COVID-19 住院患者的营养信息非常有限。我们的目的是:(1) 调查由评分营养风险筛查(NRS 2002)定义的营养风险发生率,以及由预后营养指数(PNI)和控制营养状况评分(CONUT)评估的营养不良发生率;(2) 观察营养干预情况;(3) 探讨危重症和死亡率的预测因素。根据 PNI 和 CONUT,464 名患者的营养风险为 53.00%,营养不良发生率分别为 79.09% 和 88.79%。超敏 C 反应蛋白(hs-CRP)、血小板与淋巴细胞比值(PLR)、PNI、中性粒细胞/淋巴细胞比值(NLR)、全身免疫炎症指数(SII)和 CONUT 的接收器操作特征曲线下面积分别为 0.714、0.677、0.243、0.778、0.742 和 0.743。hs-CRP、PLR、PNI、NLR、SII 和 CONUT 的死亡率相关曲线下面积分别为 0.740、0.647、0.247、0.814、0.758 和 0.767。结果表明,CONUT 和 NLR 与临界状态显著相关。我们的研究显示,COVID-19 住院患者中营养风险和营养不良的发生率较高。NLR、PLR、hs-CRP、SII 和 CONUT 是危重症和死亡率的独立预测因子。CONUT和NLR可帮助临床医生识别危重病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of malnutrition by objective nutritional indexes and predictors in hospitalized patients with COVID-19.

Nutritional information on hospitalized patients with COVID-19 is limited. We aimed to (1) investigate the prevalence of nutrition risk defined by the Scored Nutritional Risk Screening (NRS 2002) and malnutrition assessed by prognostic nutritional index (PNI) and controlling nutritional status score (CONUT), (2) observe the nutritional intervention, and (3) explore the predictors of critical condition and mortality. Nutritional risk was 53.00% and the prevalence of malnutrition was 79.09% and 88.79% among 464 patients based on PNI and CONUT, respectively. The area under the receiver operating characteristic curve for hypersensitivity C-reactive protein (hs-CRP), platelet-to-lymphocyte ratio (PLR), PNI, neutrophil/lymphocyte ratio (NLR), systemic immune-inflammation index (SII), and CONUT were 0.714, 0.677, 0.243, 0.778, 0.742, and 0.743, respectively, in discerning critical patients. The mortality-related area under the curve of hs-CRP, PLR, PNI, NLR, SII, and CONUT were 0.740, 0.647, 0.247, 0.814, 0.758, and 0.767, respectively. The results showed that CONUT and NLR were significantly correlated with the critical conditions. Our study revealed a high prevalence of nutritional risk and malnutrition among hospitalized patients with COVID-19. NLR, PLR, hs-CRP, SII, and CONUT are independent predictors of critical conditions and mortality. CONUT and NLR could assist clinicians in discerning critical cases.

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来源期刊
CiteScore
4.30
自引率
8.30%
发文量
57
审稿时长
6-12 weeks
期刊介绍: Journal of Clinical Biochemistry and Nutrition (JCBN) is an international, interdisciplinary publication encompassing chemical, biochemical, physiological, pathological, toxicological and medical approaches to research on lipid peroxidation, free radicals, oxidative stress and nutrition. The Journal welcomes original contributions dealing with all aspects of clinical biochemistry and clinical nutrition including both in vitro and in vivo studies.
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