小儿 HeartMate 3™,一名 14 岁患者 22 个月的顺利移植历程--儿童延长 LVAD 支持的时机已到?

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Clemens Haselmann, Sonja Budäus, Michael Zellner, Robert Cesnjevar, Martin Schweiger
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引用次数: 0

摘要

我们报告了一名 14 岁患者的情况,他使用 ic-LVAD 支持了近两年的时间,并在没有出现任何并发症的情况下完成了移植手术。虽然体重不超过 20 公斤的儿童也能获得机械辅助装置的支持,但仅限于体外辅助装置。对于体重合适的婴儿来说,时间内(ic)左心室辅助装置(LVAD)是一种可行的选择,可作为移植手术的桥梁,在这类婴儿中,他们占移植候选者的50%以上。一名体重 59 公斤的青少年新近被诊断出患有 DCM,并被列入心脏移植名单。在最初使用 VA-ECMO 后,开始使用雅培 HeartMate 3 LVAD,并在术后提供临时 RVAD 支持。RV 支持维持了 10 天。术后恢复顺利,他于第 98 天出院。在同学和学校负责人员的广泛培训下,他定期到门诊部就诊,并重新融入了学校的日常生活。经过总共 672 天的支持,他成功地完成了移植。虽然患者在学校参加了体育课,但没有发生意外入院、血栓或出血事件,也没有发生驱动线感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Paediatric HeartMate 3™, the Uneventful 22-Month Journey to Transplantation of a 14-Year-Old-Patient-Time for Prolonged LVAD Support in Children?

We report on a 14-year-old patient who was supported for nearly two years with an ic-LVAD and managed to complete his journey to transplantation without a single complication. Although mechanical assist device support is available for children up to 20 kg in body weight, availability is limited to paracorporeal devices. Intracorporal (ic) left ventricular assist devices (LVADs) for infants in the suitable weight class are a viable option as a bridge-to-transplant, where they make up more than 50% of transplant candidates in their category. A teenager with 59 kg body weight was newly diagnosed with DCM and listed for heart transplantation. After initially being on VA-ECMO, an Abbott HeartMate 3 LVAD with postoperative temporary RVAD support was initialised. RV-support was maintained for 10 days. The further postoperative course was uneventful, and he was discharged on day 98. He was seen regularly in the outpatient department and integrated into school routine again, following the extensive training of his classmates and the responsible school staff. After a total of 672 days on support, he was successfully transplanted. There were no unplanned admissions, thrombotic nor bleeding events, as well as no driveline infection, even though the patient participated in sport classes at school.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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