源于患者的嗅鞘细胞瘤类器官模型。

IF 7.2 2区医学 Q1 OTORHINOLARYNGOLOGY

International Forum of Allergy & Rhinology Pub Date : 2024-09-27 DOI:10.1002/alr.23464

John B Finlay, Ralph Abi Hachem, Patrick Codd, Bradley J Goldstein

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引用次数: 0

摘要

要点：我们建立了人类嗅觉鞘细胞肿瘤的培养模型。培养的器官组织类似于正常的鞘状细胞。实验表明，该模型为研究这些神经胶质细胞在维持外周嗅觉系统中的作用提供了一种工具。

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Patient-derived organoid model of olfactory ensheathing cell tumor.

Key points: We developed a culture model of a human olfactory ensheathing cell tumor. Cultured organoids resemble normal ensheathing cells. Assays suggest that this model provides a tool for studying the roles of these glial cells in the maintenance of the peripheral olfactory system.

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来源期刊

International Forum of Allergy & Rhinology OTORHINOLARYNGOLOGY-

CiteScore

11.70

自引率

10.90%

发文量

185

审稿时长

6-12 weeks

期刊介绍： International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy. International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.