Leonardo De Luca , Aldo Pietro Maggioni , Claudio Cavallini , Sergio Leonardi , Donata Lucci , Alice Sacco , Fortunato Scotto di Uccio , Serafina Valente , Alessandro Navazio , Vittorio Pascale , Giovanna Geraci , Francesca Lanni , Michele Massimo Gulizia , Furio Colivicchi , Domenico Gabrielli , Fabrizio Oliva , on behalf of the EYESHOT-2 Investigators
{"title":"心脏护理病房收治的急性心肌梗死患者的临床概况和管理：EYESHOT-2 登记。","authors":"Leonardo De Luca , Aldo Pietro Maggioni , Claudio Cavallini , Sergio Leonardi , Donata Lucci , Alice Sacco , Fortunato Scotto di Uccio , Serafina Valente , Alessandro Navazio , Vittorio Pascale , Giovanna Geraci , Francesca Lanni , Michele Massimo Gulizia , Furio Colivicchi , Domenico Gabrielli , Fabrizio Oliva , on behalf of the EYESHOT-2 Investigators","doi":"10.1016/j.ijcard.2024.132601","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The clinical governance of patients with acute myocardial infarction (AMI) has markedly changed in the last few years. We sought to assess the contemporary in-hospital management patterns of patients with AMI at a country level.</div></div><div><h3>Methods</h3><div>EYESHOT (EmploYEd antithrombotic therapies in patients with acute coronary Syndromes HOspitalized in iTalian cardiac care units)-2 was a nationwide, prospective registry aimed to evaluate the current management of patients admitted to intensive cardiac care units (CCUs) for an AMI in Italy.</div></div><div><h3>Results</h3><div>Over a 4-week period (February 1st-29th, 2024), 183 CCUs enrolled 2806 consecutive patients: 52.6 % with non-ST elevation myocardial infarction (NSTEMI) and 47.4 % with ST-elevation myocardial infarction (STEMI). The median time from hospital admission to angiography in NSTEMI was 22.3 h (IQR 10.9–46.1), while for STEMI was 1.1 h (IQR 0.5–2.2) with significant difference between hospitals with and without catheterization laboratories. In both NSTEMI and STEMI patients, percutaneous coronary intervention (PCI) was the preferred management strategy (73.3 % and 94.2 %, respectively). An optimal secondary prevention therapy, including dual antiplatelet therapy, inhibition of the renin-angiotensin system, a beta-blocker and a high-intensity statin was prescribed at discharge in more than 75 % of patients with AMI. In-hospital major bleedings occurred in 2.0 % and 2.3 % (<em>p</em> = 0.58), while death in 1.8 % and 2.8 % (<em>p</em> = 0.09) of NSTEMI and STEMI patients, respectively.</div></div><div><h3>Conclusions</h3><div>The EYESHOT-2 registry shows the current management strategies and outcome of AMI patients admitted to Italian CCUs and provides insights to improve the clinical care of such patients.</div><div><strong>Clinical Trial Registration</strong>. URL: <span><span>http://www.clinicaltrials.gov</span><svg><path></path></svg></span>. Unique identifier: <span><span>NCT06316128</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical profile and management of patients with acute myocardial infarction admitted to cardiac care units: The EYESHOT-2 registry\",\"authors\":\"Leonardo De Luca , Aldo Pietro Maggioni , Claudio Cavallini , Sergio Leonardi , Donata Lucci , Alice Sacco , Fortunato Scotto di Uccio , Serafina Valente , Alessandro Navazio , Vittorio Pascale , Giovanna Geraci , Francesca Lanni , Michele Massimo Gulizia , Furio Colivicchi , Domenico Gabrielli , Fabrizio Oliva , on behalf of the EYESHOT-2 Investigators\",\"doi\":\"10.1016/j.ijcard.2024.132601\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>The clinical governance of patients with acute myocardial infarction (AMI) has markedly changed in the last few years. We sought to assess the contemporary in-hospital management patterns of patients with AMI at a country level.</div></div><div><h3>Methods</h3><div>EYESHOT (EmploYEd antithrombotic therapies in patients with acute coronary Syndromes HOspitalized in iTalian cardiac care units)-2 was a nationwide, prospective registry aimed to evaluate the current management of patients admitted to intensive cardiac care units (CCUs) for an AMI in Italy.</div></div><div><h3>Results</h3><div>Over a 4-week period (February 1st-29th, 2024), 183 CCUs enrolled 2806 consecutive patients: 52.6 % with non-ST elevation myocardial infarction (NSTEMI) and 47.4 % with ST-elevation myocardial infarction (STEMI). The median time from hospital admission to angiography in NSTEMI was 22.3 h (IQR 10.9–46.1), while for STEMI was 1.1 h (IQR 0.5–2.2) with significant difference between hospitals with and without catheterization laboratories. In both NSTEMI and STEMI patients, percutaneous coronary intervention (PCI) was the preferred management strategy (73.3 % and 94.2 %, respectively). An optimal secondary prevention therapy, including dual antiplatelet therapy, inhibition of the renin-angiotensin system, a beta-blocker and a high-intensity statin was prescribed at discharge in more than 75 % of patients with AMI. In-hospital major bleedings occurred in 2.0 % and 2.3 % (<em>p</em> = 0.58), while death in 1.8 % and 2.8 % (<em>p</em> = 0.09) of NSTEMI and STEMI patients, respectively.</div></div><div><h3>Conclusions</h3><div>The EYESHOT-2 registry shows the current management strategies and outcome of AMI patients admitted to Italian CCUs and provides insights to improve the clinical care of such patients.</div><div><strong>Clinical Trial Registration</strong>. URL: <span><span>http://www.clinicaltrials.gov</span><svg><path></path></svg></span>. 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Clinical profile and management of patients with acute myocardial infarction admitted to cardiac care units: The EYESHOT-2 registry
Background
The clinical governance of patients with acute myocardial infarction (AMI) has markedly changed in the last few years. We sought to assess the contemporary in-hospital management patterns of patients with AMI at a country level.
Methods
EYESHOT (EmploYEd antithrombotic therapies in patients with acute coronary Syndromes HOspitalized in iTalian cardiac care units)-2 was a nationwide, prospective registry aimed to evaluate the current management of patients admitted to intensive cardiac care units (CCUs) for an AMI in Italy.
Results
Over a 4-week period (February 1st-29th, 2024), 183 CCUs enrolled 2806 consecutive patients: 52.6 % with non-ST elevation myocardial infarction (NSTEMI) and 47.4 % with ST-elevation myocardial infarction (STEMI). The median time from hospital admission to angiography in NSTEMI was 22.3 h (IQR 10.9–46.1), while for STEMI was 1.1 h (IQR 0.5–2.2) with significant difference between hospitals with and without catheterization laboratories. In both NSTEMI and STEMI patients, percutaneous coronary intervention (PCI) was the preferred management strategy (73.3 % and 94.2 %, respectively). An optimal secondary prevention therapy, including dual antiplatelet therapy, inhibition of the renin-angiotensin system, a beta-blocker and a high-intensity statin was prescribed at discharge in more than 75 % of patients with AMI. In-hospital major bleedings occurred in 2.0 % and 2.3 % (p = 0.58), while death in 1.8 % and 2.8 % (p = 0.09) of NSTEMI and STEMI patients, respectively.
Conclusions
The EYESHOT-2 registry shows the current management strategies and outcome of AMI patients admitted to Italian CCUs and provides insights to improve the clinical care of such patients.
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