噬菌体疗法临床试验现状。

Chidiebere F Uchechukwu, Adedayo Shonekan
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引用次数: 0

摘要

最近,噬菌体被认为是抗菌疗法的替代品。由于细菌能够适应并发展出抵御抗生素的防御机制,传染病继续困扰着全世界。抗生素耐药细菌感染的发病率不断上升,因此有必要在全球范围内开发治疗细菌感染的新技术。临床试验表明,抗生素对耐药细菌的疗效显著。然而,科学家们在未来的临床试验中应仔细研究噬菌体抗药性的影响,评估与抗菌剂的组合策略,并解决噬菌体疗法实施过程中的挑战,以有效实施噬菌体疗法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current status of clinical trials for phage therapy.

Recently, bacteriophages have been considered alternatives to antibacterial treatments. Infectious diseases continue to plague the world because bacteria can adapt and develop defence mechanisms against antibiotics. The growing incidence of antibiotic-resistant bacterial infections necessitated the development of new techniques for treating bacterial infections worldwide. Clinical trials have shown efficiency against antibiotic-resistant bacteria. However, scientists in future clinical trials should scrutinize phage resistance implications, assess combination strategies with antimicrobial agents and address challenges in phage therapy delivery for effective implementation.

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