揭开 SARS-CoV-2 的凝血阴谋：Spike 的作用。

IF 13.1 1区医学 Q1 IMMUNOLOGY

Trends in Immunology Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI:10.1016/j.it.2024.09.007

Tom Aschman, Helena Radbruch

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引用次数: 0

摘要

Ryu 等人最近的研究表明，SARS-CoV-2 Spike 蛋白能与纤维蛋白（ogen）结合，影响小鼠的凝血和免疫反应。在这篇聚焦文章中，我们将重点讨论所述对自然杀伤（NK）细胞反应的影响，以及将其转化为针对 COVID-19 的潜在新治疗靶点的建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Unmasking SARS-CoV-2's coagulation conspiracy: the role of Spike.

The recent study by Ryu et al. demonstrates that the SARS-CoV-2 Spike protein binds fibrin(ogen), impacting coagulation and immune responses in mice. In this spotlight article we focus on the described effects on natural killer (NK) cell responses as well as the suggested translation into potential new therapeutic targets against COVID-19.

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来源期刊

Trends in Immunology 医学-免疫学

CiteScore

25.10

自引率

0.60%

发文量

130

审稿时长

6-12 weeks

期刊介绍： Trends in Immunology serves as a vital platform for tracking advancements across various areas of immunology, offering concise reviews and hypothesis-driven viewpoints in each issue. With additional sections providing comprehensive coverage, the journal offers a holistic view of immunology. This broad perspective makes it an invaluable resource for researchers, educators, and students, facilitating the connection between basic and clinical immunology. Recognized as one of the top monthly review journals in its field, Trends in Immunology is highly regarded by the scientific community.