牛高致病性禽流感病毒在牛奶副产品乳糖中的稳定性和失活。

IF 3.8 3区医学 Q2 VIROLOGY

Viruses-Basel Pub Date : 2024-09-12 DOI:10.3390/v16091451

Taeyong Kwon, Jordan T Gebhardt, Eu Lim Lyoo, Mohammed Nooruzzaman, Natasha N Gaudreault, Igor Morozov, Diego G Diel, Juergen A Richt

{"title":"牛高致病性禽流感病毒在牛奶副产品乳糖中的稳定性和失活。","authors":"Taeyong Kwon, Jordan T Gebhardt, Eu Lim Lyoo, Mohammed Nooruzzaman, Natasha N Gaudreault, Igor Morozov, Diego G Diel, Juergen A Richt","doi":"10.3390/v16091451","DOIUrl":null,"url":null,"abstract":"The recent incursion of highly pathogenic influenza viruses into dairy cattle opens new insights for influenza virus ecology and its interspecies transmission and may have a significant impact on public health and agriculture. The aim of this study was to determine the stability of a bovine highly pathogenic avian influenza H5N1 virus isolate in the milk byproduct lactose and to evaluate two inactivation methods using industrial procedures. The bovine isolate of the highly pathogenic avian influenza H5N1 virus was stable for 14 days in a concentrated lactose solution under refrigerated conditions. Heat or citric acid treatments successfully inactivated the virus in lactose. This study highlights the persistence of HPAIV in lactose and its efficient inactivation under industrial standards.","PeriodicalId":49328,"journal":{"name":"Viruses-Basel","volume":null,"pages":null},"PeriodicalIF":3.8000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11437424/pdf/","citationCount":"0","resultStr":"{\"title\":\"Bovine Highly Pathogenic Avian Influenza Virus Stability and Inactivation in the Milk Byproduct Lactose.\",\"authors\":\"Taeyong Kwon, Jordan T Gebhardt, Eu Lim Lyoo, Mohammed Nooruzzaman, Natasha N Gaudreault, Igor Morozov, Diego G Diel, Juergen A Richt\",\"doi\":\"10.3390/v16091451\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The recent incursion of highly pathogenic influenza viruses into dairy cattle opens new insights for influenza virus ecology and its interspecies transmission and may have a significant impact on public health and agriculture. The aim of this study was to determine the stability of a bovine highly pathogenic avian influenza H5N1 virus isolate in the milk byproduct lactose and to evaluate two inactivation methods using industrial procedures. The bovine isolate of the highly pathogenic avian influenza H5N1 virus was stable for 14 days in a concentrated lactose solution under refrigerated conditions. Heat or citric acid treatments successfully inactivated the virus in lactose. This study highlights the persistence of HPAIV in lactose and its efficient inactivation under industrial standards.\",\"PeriodicalId\":49328,\"journal\":{\"name\":\"Viruses-Basel\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11437424/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Viruses-Basel\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/v16091451\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VIROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Viruses-Basel","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/v16091451","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VIROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

最近，高致病性流感病毒侵入奶牛体内，这为流感病毒生态学及其种间传播提供了新的视角，并可能对公共卫生和农业产生重大影响。本研究的目的是确定牛高致病性禽流感 H5N1 病毒分离物在牛奶副产品乳糖中的稳定性，并评估使用工业程序的两种灭活方法。在冷藏条件下，牛分离的高致病性禽流感 H5N1 病毒在浓缩乳糖溶液中稳定存在 14 天。加热或柠檬酸处理可成功灭活乳糖中的病毒。这项研究强调了高致病性禽流感病毒在乳糖中的持久性及其在工业标准下的高效灭活。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Bovine Highly Pathogenic Avian Influenza Virus Stability and Inactivation in the Milk Byproduct Lactose.

The recent incursion of highly pathogenic influenza viruses into dairy cattle opens new insights for influenza virus ecology and its interspecies transmission and may have a significant impact on public health and agriculture. The aim of this study was to determine the stability of a bovine highly pathogenic avian influenza H5N1 virus isolate in the milk byproduct lactose and to evaluate two inactivation methods using industrial procedures. The bovine isolate of the highly pathogenic avian influenza H5N1 virus was stable for 14 days in a concentrated lactose solution under refrigerated conditions. Heat or citric acid treatments successfully inactivated the virus in lactose. This study highlights the persistence of HPAIV in lactose and its efficient inactivation under industrial standards.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Viruses-Basel VIROLOGY-

CiteScore

7.30

自引率

12.80%

发文量

2445

审稿时长

1 months

期刊介绍： Viruses (ISSN 1999-4915) is an open access journal which provides an advanced forum for studies of viruses. It publishes reviews, regular research papers, communications, conference reports and short notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. We also encourage the publication of timely reviews and commentaries on topics of interest to the virology community and feature highlights from the virology literature in the ''News and Views'' section. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.