坎帕拉市年轻女性的饮酒情况:将自述调查数据与尿液中存在的乙基葡萄糖醛酸代谢物进行比较。

3区 综合性期刊
Monica H Swahn, Jane Palmier, Rachel Culbreth, Godfrey S Bbosa, Charles Natuhamya, Gideon Matovu, Rogers Kasirye
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引用次数: 0

摘要

本研究旨在确定居住在坎帕拉市区的女性自我报告的饮酒情况与尿液中乙型葡萄糖醛酸(EtG)代谢物含量之间的一致程度。2023 年,我们招募了 300 名 18-24 岁的年轻女性参加一项前瞻性队列研究,在坎帕拉市区的三个地点(即班达(Banda)、布韦塞(Bwaise)和马金迪耶(Makindye))研究精神疾病的机理途径。作为基线评估的一部分,参与者被要求填写一份由研究助理主持的调查问卷,并提供一份尿样,以筛查包括 EtG 在内的 16 种不同物质和/或其代谢物。总体而言,58%(n = 174)的受试者表示曾经饮酒,23%(n = 68)的受试者表示在过去一个月中曾饮酒。在 300 名女性中,10%(n = 30)的尿样中含有 EtG,其中 40%(n = 12)称从未饮酒(p = 0.035)。在这项研究中,近期饮酒的女性相对较少。然而,自我报告的饮酒情况与 EtG 存在之间的不一致,让人担心自我报告饮酒情况的准确性。还需要进行更多的研究,以了解自我报告的饮酒情况、社会期望以及对坎帕拉城市年轻女性的酒精预防和干预策略的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alcohol Use among Young Women in Kampala City: Comparing Self-Reported Survey Data with Presence of Urinary Ethyl Glucuronide Metabolite.

This study sought to determine the level of concordance between self-reported alcohol use and the presence of its urinary ethyl glucuronide (EtG) metabolite in women living in urban Kampala. In 2023, we recruited 300 young women, ages 18 to 24 years, to participate in a prospective cohort study across three sites in urban Kampala (i.e., Banda, Bwaise, and Makindye) to examine the mechanistic pathways of mental illness. As part of the baseline assessment, participants were asked to complete a research assistant-administered survey and to provide a urine sample to screen for 16 different substances and/or their metabolites, including EtG. Overall, 58% (n = 174) reported to have ever consumed alcohol and 23% (n = 68) to have used it in the past month. Among the 300 women, 10% (n = 30) had EtG levels in their urine sample and of these, 40% (n = 12) reported to have never consumed alcohol, using a self-reported survey (p = 0.035). Recent alcohol use was relatively low among the women in this study. However, the discordance between self-reported alcohol use and the presence of EtG presents concerns about the accuracy of self-reported alcohol use. Additional research is needed to contextualize self-reported alcohol use, social desirability, and the implications for alcohol prevention and intervention strategies for young women in urban Kampala.

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来源期刊
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期刊介绍: International Journal of Environmental Research and Public Health (IJERPH) (ISSN 1660-4601) is a peer-reviewed scientific journal that publishes original articles, critical reviews, research notes, and short communications in the interdisciplinary area of environmental health sciences and public health. It links several scientific disciplines including biology, biochemistry, biotechnology, cellular and molecular biology, chemistry, computer science, ecology, engineering, epidemiology, genetics, immunology, microbiology, oncology, pathology, pharmacology, and toxicology, in an integrated fashion, to address critical issues related to environmental quality and public health. Therefore, IJERPH focuses on the publication of scientific and technical information on the impacts of natural phenomena and anthropogenic factors on the quality of our environment, the interrelationships between environmental health and the quality of life, as well as the socio-cultural, political, economic, and legal considerations related to environmental stewardship and public health. The 2018 IJERPH Outstanding Reviewer Award has been launched! This award acknowledge those who have generously dedicated their time to review manuscripts submitted to IJERPH. See full details at http://www.mdpi.com/journal/ijerph/awards.
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