{"title":"治疗用合成阴离子转运体","authors":"Elba Feo, Philip A. Gale","doi":"10.1016/j.cbpa.2024.102535","DOIUrl":null,"url":null,"abstract":"<div><div>This short review highlights recent examples of small-molecule anion transporters reported in the literature that have potentially useful biological activity. This includes anionophores with antibiotic or antifungal activity, anticancer activity, or the potential to treat channelopathies such as cystic fibrosis. Additionally selective and targeted anion transporters are also discussed.</div></div>","PeriodicalId":291,"journal":{"name":"Current Opinion in Chemical Biology","volume":"83 ","pages":"Article 102535"},"PeriodicalIF":6.9000,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Therapeutic synthetic anion transporters\",\"authors\":\"Elba Feo, Philip A. Gale\",\"doi\":\"10.1016/j.cbpa.2024.102535\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>This short review highlights recent examples of small-molecule anion transporters reported in the literature that have potentially useful biological activity. This includes anionophores with antibiotic or antifungal activity, anticancer activity, or the potential to treat channelopathies such as cystic fibrosis. Additionally selective and targeted anion transporters are also discussed.</div></div>\",\"PeriodicalId\":291,\"journal\":{\"name\":\"Current Opinion in Chemical Biology\",\"volume\":\"83 \",\"pages\":\"Article 102535\"},\"PeriodicalIF\":6.9000,\"publicationDate\":\"2024-09-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Chemical Biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S136759312400111X\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Chemical Biology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S136759312400111X","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
This short review highlights recent examples of small-molecule anion transporters reported in the literature that have potentially useful biological activity. This includes anionophores with antibiotic or antifungal activity, anticancer activity, or the potential to treat channelopathies such as cystic fibrosis. Additionally selective and targeted anion transporters are also discussed.
期刊介绍:
COCHBI (Current Opinion in Chemical Biology) is a systematic review journal designed to offer specialists a unique and educational platform. Its goal is to help professionals stay informed about the growing volume of information in the field of Chemical Biology through systematic reviews.