对生殖调节 NOD 样受体的深入了解

IF 12.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Structural & Molecular Biology Pub Date : 2024-10-08 DOI:10.1038/s41594-024-01383-7

Inga V. Hochheiser, Matthias Geyer

引用次数: 0

摘要

未被充分研究的 NOD 样受体亚群与生殖系统有关，它们的功能障碍可导致不育。最近获得的围绕NLRP5的核心皮层下母体复合物结构，为我们深入了解早期胚胎细胞质晶格的这一组成部分提供了重要线索。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Insights into reproduction-regulating NOD-like receptors

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Insights into reproduction-regulating NOD-like receptors

An understudied subset of NOD-like receptors are involved in the reproductive system, and their dysfunction can cause infertility. The recently obtained structures of the core subcortical maternal complex assembled around one of them, NLRP5, provide important insight into this building block of early embryo cytoplasmic lattices.

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来源期刊

Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS

CiteScore

22.00

自引率

1.80%

发文量

160

审稿时长

3-8 weeks

期刊介绍： Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.