用于诊断病毒性肝炎的纳米粒子驱动生物传感器

IF 11.8 1区化学 Q1 CHEMISTRY, ANALYTICAL

Trends in Analytical Chemistry Pub Date : 2024-09-24 DOI:10.1016/j.trac.2024.117985

Chenggong Zhu , Zhen Xun , Ruijie Fu , Qunfang Huang , Qishui Ou , Yunlei Xianyu , Can Liu

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引用次数: 0

摘要

快速准确的实验室诊断对于有效控制病毒性肝炎至关重要。随着纳米技术的发展，基于纳米粒子的生物传感器在病毒性肝炎诊断中的应用引起了广泛关注。纳米粒子具有优异的物理化学特性，如巨大的比表面积、较高的表面能、较强的导电性以及尺寸和结构的易改性，这些特性赋予了生物传感器优异的性能。在这篇综述中，我们总结了病毒性肝炎实验室诊断领域的最新进展，重点介绍了基于纳米粒子的生物传感器在病毒生物标志物和肝功能生物标志物鉴定中的应用。此外，我们还讨论了基于纳米粒子的生物传感器在病毒性肝炎诊断中目前面临的挑战和未来前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Nanoparticle-driven biosensors for diagnosis of viral hepatitis

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Nanoparticle-driven biosensors for diagnosis of viral hepatitis

Rapid and accurate laboratory diagnosis are essential for the effective control of viral hepatitis. With the advances in nanotechnology, the application of nanoparticle-based biosensors for the diagnosis of viral hepatitis has attracted extensive attention. The excellent physicochemical properties of nanoparticles, such as extensive specific surface area, heightened surface energy, enhanced electrical conductivity, and facile size and structural modifiability, confer exceptional performance on biosensors. In this review, we summarize the latest advances in the field of laboratory diagnosis for viral hepatitis, focusing on the use of nanoparticle-based biosensors in the identification of viral biomarkers and liver function biomarkers. Additionally, we discuss current challenges and future prospects of nanoparticle-based biosensors in the diagnosis of viral hepatitis.

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来源期刊

Trends in Analytical Chemistry 化学-分析化学

CiteScore

20.00

自引率

4.60%

发文量

257

审稿时长

3.4 months

期刊介绍： TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.