前列腺癌中雄激素受体的特异性靶向作用

IF 31.7 1区生物学 Q1 GENETICS & HEREDITY

Nature genetics Pub Date : 2024-09-27 DOI:10.1038/s41588-024-01935-z

Cory Abate-Shen

引用次数: 0

摘要

雄激素受体的辅助因子 NSD2 可帮助人们深入了解雄激素受体在特定环境下的功能，是一个新的干预目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Context-specific targeting of the androgen receptor in prostate cancer

查看原文本刊更多论文

Context-specific targeting of the androgen receptor in prostate cancer

A co-factor for the androgen receptor, NSD2, provides insights into context-specific functions of the androgen receptor and is a new target for intervention.

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来源期刊

Nature genetics 生物-遗传学

CiteScore

43.00

自引率

2.60%

发文量

241

审稿时长

3 months

期刊介绍： Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. Integrative genetic topics comprise, but are not limited to: -Genes in the pathology of human disease -Molecular analysis of simple and complex genetic traits -Cancer genetics -Agricultural genomics -Developmental genetics -Regulatory variation in gene expression -Strategies and technologies for extracting function from genomic data -Pharmacological genomics -Genome evolution