静脉曲张带结扎术和卡维地洛：永远在一起，还是不在一起？

IF 23 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gut Pub Date : 2024-09-25 DOI:10.1136/gutjnl-2024-333643

Philip D J Dunne, Ewan H Forrest, Adrian J Stanley

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引用次数: 0

摘要

我们对 Tevethia 等人最近发表的 "CAVARLY 试验 "表示祝贺，该试验表明，在减少高危静脉曲张患者首次食管静脉曲张出血（OVB）方面，静脉曲张带结扎术（VBL）和卡维地洛联合治疗优于单独使用 VBL 或卡维地洛。尽管联合疗法组的 OVB 发生率和死亡率明显较低，但疾病严重程度的其他指标，如腹水进展、...

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Variceal band ligation and carvedilol: together forever, or not?

We extend our congratulations to Tevethia et al for their recently published ‘CAVARLY trial’, which suggests the combination of variceal band ligation (VBL) and carvedilol is superior to VBL or carvedilol alone in the reduction of the first episode of oesophageal variceal bleeding (OVB) in patients with high-risk varices.1 This is the first primary prophylaxis randomised control trial to examine combination therapy and provides some interesting results which require further thought. Despite significantly lower rates of OVB and mortality in the combination therapy group, other indicators of disease severity such as; progression of ascites, …

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来源期刊

Gut 医学-胃肠肝病学

CiteScore

45.70

自引率

2.40%

发文量

284

审稿时长

1.5 months

期刊介绍： Gut is a renowned international journal specializing in gastroenterology and hepatology, known for its high-quality clinical research covering the alimentary tract, liver, biliary tree, and pancreas. It offers authoritative and current coverage across all aspects of gastroenterology and hepatology, featuring articles on emerging disease mechanisms and innovative diagnostic and therapeutic approaches authored by leading experts. As the flagship journal of BMJ's gastroenterology portfolio, Gut is accompanied by two companion journals: Frontline Gastroenterology, focusing on education and practice-oriented papers, and BMJ Open Gastroenterology for open access original research.