卵巢性发育障碍（DSD）：性发育障碍老年男性患者腹膜癌变的罕见病例

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2024-09-24 DOI:10.1016/j.gore.2024.101515

Anastasia Navitski , Sakshi Sehgal , Kalyani Ballur , Lawrence C. Layman , Robert V. Higgins

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引用次数: 0

摘要

性发育障碍（DSDs）是以性腺和/或生殖器发育不典型为特征的一系列疾病。其发病率为每 5,000 名活产婴儿中就有 1 例。DSD患者罹患性腺和生殖道肿瘤的风险可能会增加。本报告总结了目前有关 DSD 患者性腺肿瘤风险的知识。具体而言，我们将重点关注卵睾DSD（OT-DSD），它占DSD病例的5%，其定义是在同一个人身上同时存在卵巢和睾丸组织。我们介绍了一例罕见的表型为男性 XY 的 OT-DSD 患者，他在 71 岁时被诊断出患有侵袭性腹膜癌。

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Ovotesticular Disorders of sexual development (DSD): A rare case of peritoneal carcinomatosis in an elderly DSD male patient

Disorders of sexual development (DSDs) represent a spectrum of conditions characterized by atypical gonadal and/or genital development. The incidence is 1 in 5,000 live births. Patients with DSD may be at increased risk for developing gonadal and reproductive tract tumors. This report summarizes the current knowledge on the risks of gonadal tumors in patients with DSD. Specifically, we focus on ovotesticular DSD (OT-DSD), which accounts for 5% of DSD cases and is defined by the presence of both ovarian and testicular tissues in the same individual. We present a rare case of a phenotypically male XY patient with OT-DSD who was diagnosed with aggressive peritoneal cancer at the age of 71.

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.