克里斯托弗-雷德曼 MB Bchir、FRCP、FRCOG 教授(临时),1941 年 11 月 30 日至 2024 年 8 月 13 日

IF 4.7 1区 医学 Q1 OBSTETRICS & GYNECOLOGY
Manu Vatish, Aris T. Papageorghiou
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引用次数: 0

摘要

克里斯托弗(克里斯)-雷德曼(Christopher (Chris) Redman)教授作为一名杰出的产科先驱和教授,在82岁高龄时去世,社会各界对此深表哀悼。克里斯对知识的不懈追求以及他对妇女和新生儿健康的贡献,给这一领域以及所有有幸与他并肩工作的人留下了不可磨灭的印记。克里斯1941年出生于南非,父亲是一名天文学家,这影响了他的早年生活,后来他举家迁往英国,并在剑桥的文法学校就读。从剑桥大学到牛津大学临床医学院的求学之路,点燃了他对医学研究的热情,这也决定了他的职业生涯。他的临床旅程将他带到了美国巴尔的摩的约翰霍普金斯大学、谢菲尔德大学,然后又回到了牛津大学,并加入了牛津大学Regius医学系。他首次涉足产科研究是一项关于甲基多巴治疗妊娠期中度高血压疗效的临床试验,结果显示胎儿丢失减少,而这并非由于子痫前期发病率降低所致。他证明了这种药物对胎儿生长没有不良影响,证实了在孕期使用这种药物是安全的。从那时起,克里斯的职业生涯开始专注于子痫前期,他领导了关于胎盘释放的细胞外囊泡在子痫前期发病机制中的作用的开创性研究。他在改善母亲预后的同时并没有改善胎儿的预后,最终与杰弗里-道斯(Geoffrey Dawes)教授一起创建了首个产前胎儿心率分析计算机系统。该系统现已在全球范围内使用,彻底改变了孕产妇和胎儿医学的临床实践和决策,证明了他的远见卓识和对患者护理的不懈追求。克里斯于 1983 年创办了他的高风险诊所,他对病人的承诺使他们于 1988 年成立了银星慈善机构,为该科室和他的研究工作筹集资金。在取得学术成就的同时,克里斯于1991年与先兆子痫幸存者和患者倡导者伊泽贝尔-沃克(Isobel Walker)共同创立了先兆子痫行动组织(Action on Preeclampsia),该慈善组织极大地改善了对先兆子痫的护理并提高了人们对该疾病的认识。他发表了无数演讲,并出版了全面的患者指南。他对社区参与的承诺反映了他对生活的热情,表现在他热衷于马拉松长跑、徒步旅行、交谊舞和骑自行车上班,这些活动让他保持了活力和良好的人际关系。在牛津大学,克里斯度过了他大部分的职业生涯,他不仅以敏锐的智慧和开创性的研究著称,还以热情和富有感染力的个性而闻名。在牛津大学,克里斯的大部分职业生涯都是在那里度过的,他不仅以敏锐的智慧和开创性的研究而闻名,还以热情和引人入胜的个性而闻名。他善于在科学讨论中注入幽默,因此深受同事和学生的喜爱。他的医学创新和人际交往感动了无数人,他的精神将永垂不朽。克里斯托弗-雷德曼博士的妻子科琳娜(Corinna)、他们的五个孩子和 13 个孙子孙女都健在,对他们来说,他不仅是一位学者,更是一位尽职尽责的家庭主妇。当我们向他道别时,我们为他充满智慧、激情和仁慈的美好生活而庆贺。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Professor Christopher Redman MBBChir (Cantab), FRCP, FRCOG (fellowship ad eundem), 30 November 1941 to 13 August 2024

Professor Christopher Redman MBBChir (Cantab), FRCP, FRCOG (fellowship ad eundem), 30 November 1941 to 13 August 2024

With profound sadness, the community mourns the loss of Professor Christopher (Chris) Redman, who passed away at the age of 82 after a distinguished career as a pioneering obstetric physician and professor. Chris' relentless pursuit of knowledge and his contributions to the health of women and newborns left an indelible mark on the field and on all who had the privilege of working alongside him.

Born in South Africa in 1941, Chris' early years were shaped by his father's work as an astronomer, leading the family to move to the United Kingdom where he attended grammar school in Cambridge. His academic journey led him from Cambridge University to Oxford's Clinical Medical School, igniting a passion for medical research that would define his career. His clinical journey took him to Johns Hopkins University in Baltimore USA, to the University of Sheffield and then back to Oxford where he joined the Regius Department of Medicine.

Chris was a trailblazing innovator in maternal and fetal medicine. His first foray into obstetric research was a clinical trial on the efficacy of methyldopa for moderate hypertension in pregnancy where he showed a reduction in fetal loss, which was not due to a reduction in preeclampsia rates. He demonstrated that the drug had no adverse effects on fetal growth confirming that this drug was safe to use in pregnancy. From here onwards, Chris' career became focussed on preeclampsia and he led groundbreaking research into the role of extracellular vesicles released from the placenta in the pathogenesis of the condition.

His improvements in outcomes for mothers were not being matched by enhanced fetal outcomes and this culminated in the creation, alongside Professor Geoffrey Dawes, of the first computerised system for antepartum fetal heart rate analysis. This system, now used worldwide, has revolutionised clinical practice and decision-making in maternal and fetal medicine and stands as a testament to his foresight and unwavering dedication to patient care.

Chris started his high-risk clinic in 1983. Such was his commitment to his patients that they founded the Silver Star Charity in 1988 to raise funds for the unit and his research work. Even after retirement in 1998, Chris retained a major interest in driving understanding of preeclampsia and improving the Dawes-Redman algorithm, resulting in the publication of over 250 papers in this period alone, the most recent in June 2024.

In parallel with his academic achievements, Chris co-founded Action on Preeclampsia in 1991 (with Isobel Walker, a preeclampsia survivor and patient advocate), a charity that has dramatically improved care and awareness of the disease. He gave countless presentations and published comprehensive patient guides. His commitment to community engagement mirrored his zest for life, demonstrated in his enthusiasm for marathon running, hiking, ballroom dancing, and cycling to work, activities that kept him vibrant and well-connected.

At Oxford, where he spent the majority of his career, Chris was known not only for his sharp intellect and pioneering research, but also for his warm and engaging personality. He remained razor-sharp throughout, recognised for his tenacity, yet extremely supportive and endearingly funny. His ability to inject humour into scientific discussions made him a beloved figure among colleagues and students alike. His legacy will live on through the countless lives he touched, both through his medical innovations and through his personal interactions. The corridors of Oxford will be quieter without his sage advice.

Dr. Christopher Redman is survived by his wife, Corinna, their five children and 13 grandchildren, to whom he was not just a scholar but a devoted family man. As we say goodbye, we celebrate a life well-lived, full of intellect, passion and kindness.

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来源期刊
CiteScore
10.90
自引率
5.20%
发文量
345
审稿时长
3-6 weeks
期刊介绍: BJOG is an editorially independent publication owned by the Royal College of Obstetricians and Gynaecologists (RCOG). The Journal publishes original, peer-reviewed work in all areas of obstetrics and gynaecology, including contraception, urogynaecology, fertility, oncology and clinical practice. Its aim is to publish the highest quality medical research in women''s health, worldwide.
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