在器官组织中再现免疫与上皮的相互作用

IF 27.7 1区医学 Q1 IMMUNOLOGY

Nature Immunology Pub Date : 2024-09-25 DOI:10.1038/s41590-024-01967-x

Kevin Man, Axel Kallies

引用次数: 0

摘要

用一种新方法再造含有存活的组织驻留记忆 T 细胞的人体肠道器官组织，将有助于探索组织-免疫相互作用和临床相关免疫病理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Recreating immune and epithelial interactions in organoids

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Recreating immune and epithelial interactions in organoids

A novel method that recreates human intestinal organoids containing viable tissue-resident memory T cells will facilitate the exploration of tissue–immune interactions and clinically relevant immune pathologies.

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来源期刊

Nature Immunology 医学-免疫学

CiteScore

40.00

自引率

2.30%

发文量

248

审稿时长

4-8 weeks

期刊介绍： Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.