绝经后妇女的激素替代疗法方案

G. Pérez López, E. Fernández Fernández, I. Jiménez Hernando, O. González Albarrán
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引用次数: 0

摘要

激素替代疗法(HRT)是一种针对绝经后妇女的治疗方法,目的是提高生活质量,并改善在这一生命阶段出现的与激素缺乏有关的不良反应。对于大多数 60 岁以下、处于更年期早期(更年期开始后的头 10 年内)的健康女性来说,激素替代疗法的益处大于风险。在 60-70 岁年龄组开始使用 HRT,需要进行个体化的风险/效益计算,考虑其他可用药物,并采用最低有效剂量。一般情况下,70 岁以后不应开始使用激素替代疗法。雌激素制剂是目前最有效的治疗选择,添加黄体酮的目的是保护子宫完整的妇女免受全身性雌激素治疗的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Protocolo de tratamiento hormonal sustitutivo en la posmenopausia
Hormone replacement therapy (HRT) is a treatment for postmenopausal women to improve quality of life and the adverse effects associated with hormonal deficiencies that occur at this stage of life. In most healthy women under 60 years of age who are in early menopause (within the first 10 years of the onset of menopause), the benefits of HRT outweigh the risks. Initiation of HRT in the 60-70 age group requires an individualized risk/benefit calculation, consideration of other available drugs, and the lowest effective dose. HRT should generally not be started after age 70. Estrogen formulations are the most effective therapeutic option available and the addition of progesterone is intended to protect against the consequences of systemic estrogen therapy in women with intact uteruses.
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