孕期口服葡萄糖耐量筛查试验中的低血糖症与低出生体重儿。

Nicoleta Gana, Iulia Huluta, Nicolae Gica
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引用次数: 0

摘要

孕产妇低血糖是指孕妇血糖水平低于正常水平,越来越多地与不良妊娠结局相关,包括新生儿出生体重不足(LBW)。低出生体重是指新生儿出生体重低于 2500 克,可由多种因素造成,包括孕产妇营养、健康状况和代谢状况(如低血糖)。母体低血糖可能会影响胎儿的生长,改变胎儿所需的营养和氧气供应,导致胎儿发育和成长受限。这种情况不仅会对孕期造成重大风险,还会影响胎儿的长期健康,增加日后出现发育迟缓、健康问题和慢性疾病的可能性。这方面的研究主要集中在了解孕产妇低血糖影响胎儿发育的机制上,研究表明胎盘血流和营养运输的改变以及对胎儿胰岛素水平和新陈代谢的直接影响可能在其中发挥了作用。鉴于孕产妇低血糖症对新生儿健康的潜在影响,早期发现和处理低血糖症对降低低体重儿及其相关并发症的风险至关重要。要充分阐明孕产妇血糖水平与胎儿生长之间复杂的相互作用,并制定有针对性的干预措施来支持母婴健康,还需要进一步的研究。了解这些关系对于改善产前护理和低血糖并发症孕妇的预后至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hypoglycaemia in screening oral glucose tolerance test in pregnancy with low birth weight fetus.

Maternal hypoglycemia, a condition characterized by lower than normal blood glucose levels in pregnant women, has been increasingly associated with adverse pregnancy outcomes, including low birth weight (LBW) in neonates. LBW, defined as a birth weight of less than 2500 g, can result from various factors, including maternal nutrition, health status, and metabolic conditions like hypoglycemia. Maternal hypoglycemia may affect fetal growth by altering the supply of essential nutrients and oxygen to the fetus, leading to restricted fetal development and growth. This condition poses significant risks not only during pregnancy but also for the long-term health of the child, increasing the likelihood of developmental delays, health issues, and chronic conditions later in life. Research in this area has focused on understanding the mechanisms through which maternal hypoglycemia influences fetal development, with studies suggesting that alterations in placental blood flow and nutrient transport, as well as direct effects on fetal insulin levels and metabolism, may play a role. Given the potential impact of maternal hypoglycemia on neonatal health outcomes, early detection and management are crucial to minimize risks for LBW and its associated complications. Further investigations are needed to fully elucidate the complex interactions between maternal glucose levels and fetal growth, as well as to develop targeted interventions to support the health of both mother and child. Understanding these relationships is vital for improving prenatal care and outcomes for pregnancies complicated by hypoglycemia.

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