{"title":"资源匮乏地区糖尿病患者心理障碍的患病率及其对药物治疗的影响：基层医疗机构的前瞻性评估。","authors":"Kiran Shahbaz, Alamgeer, Vibhu Paudyal, Maryam Zubair, Maryam Zahra Safdar, Momina Tahir, Laraib Akram, Salamat Ali","doi":"10.2147/PPA.S463133","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Prevalence of psychological disorders among individuals with diabetes is significantly higher as compared to the general population.</p><p><strong>Aim: </strong>This study aimed to assess the prevalence and impact of psychological disorders on pharmacotherapy of diabetes patients.</p><p><strong>Methodology: </strong>This cross-sectional study was conducted at two primary care hospitals in Pakistan from April to June 2023. The nine-item Patient Health Care Questionnaire (PHQ-9) scale was used to assess depression in the study's population, and its effects on pharmacotherapy of diabetes. Chi-square test was used to evaluate relationship between ordinal variables/categorical variables and depression whereas; Student's <i>t</i>-test was used to assess the relationship between numerical variables with depression.</p><p><strong>Results: </strong>A total of 320 patients were assessed, comprising 120 (37.5%) males and 200 (62.5%) females, with a mean age of 52.5 (SD±11.8) years. The average duration of diabetes is 7.0 (SD±5.4). The average PHQ-9 score was 8.3 (SD±5.5). Depression was found to be prevalent in 43.7% of the study population. Gender (female) (<i>p-value</i> 0.002), advanced age (<i>p-value</i> 0.002), lower income (p-value 0.001), education levels (<i>p-value</i> 0.001), longer duration of diabetes (<i>p-value</i> 0.001), poor diabetes control according to BSR value (<i>p-value</i> 0.001), usage of injectable insulin (<i>p-value</i> 0.005), and concomitant diseases (<i>p-value</i> 0.001) were found to be independently linked with depression. Significant association was observed between depression and treatment adherence (<i>p-value</i> 0.0025), number of missed doses (p-value 0.045), and difficulty in diabetes management (<i>p-value</i> 0.0015).</p><p><strong>Conclusion: </strong>Our study highlights significant prevalence of depression in study population and the prevalent depression negatively impacts on treatment adherence. It also revealed that depression complicates diabetes management resulting in poor medication adherence, poor diabetes control and diabetes related complications, making diabetes control more challenging and difficult.</p>","PeriodicalId":19972,"journal":{"name":"Patient preference and adherence","volume":"18 ","pages":"1939-1948"},"PeriodicalIF":2.0000,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416907/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence and Impact of Psychological Disorders on Pharmacotherapy of Diabetic Patients in Low Resource Settings: A Prospective Assessment in Primary Healthcare Settings.\",\"authors\":\"Kiran Shahbaz, Alamgeer, Vibhu Paudyal, Maryam Zubair, Maryam Zahra Safdar, Momina Tahir, Laraib Akram, Salamat Ali\",\"doi\":\"10.2147/PPA.S463133\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Prevalence of psychological disorders among individuals with diabetes is significantly higher as compared to the general population.</p><p><strong>Aim: </strong>This study aimed to assess the prevalence and impact of psychological disorders on pharmacotherapy of diabetes patients.</p><p><strong>Methodology: </strong>This cross-sectional study was conducted at two primary care hospitals in Pakistan from April to June 2023. The nine-item Patient Health Care Questionnaire (PHQ-9) scale was used to assess depression in the study's population, and its effects on pharmacotherapy of diabetes. Chi-square test was used to evaluate relationship between ordinal variables/categorical variables and depression whereas; Student's <i>t</i>-test was used to assess the relationship between numerical variables with depression.</p><p><strong>Results: </strong>A total of 320 patients were assessed, comprising 120 (37.5%) males and 200 (62.5%) females, with a mean age of 52.5 (SD±11.8) years. The average duration of diabetes is 7.0 (SD±5.4). The average PHQ-9 score was 8.3 (SD±5.5). Depression was found to be prevalent in 43.7% of the study population. Gender (female) (<i>p-value</i> 0.002), advanced age (<i>p-value</i> 0.002), lower income (p-value 0.001), education levels (<i>p-value</i> 0.001), longer duration of diabetes (<i>p-value</i> 0.001), poor diabetes control according to BSR value (<i>p-value</i> 0.001), usage of injectable insulin (<i>p-value</i> 0.005), and concomitant diseases (<i>p-value</i> 0.001) were found to be independently linked with depression. Significant association was observed between depression and treatment adherence (<i>p-value</i> 0.0025), number of missed doses (p-value 0.045), and difficulty in diabetes management (<i>p-value</i> 0.0015).</p><p><strong>Conclusion: </strong>Our study highlights significant prevalence of depression in study population and the prevalent depression negatively impacts on treatment adherence. It also revealed that depression complicates diabetes management resulting in poor medication adherence, poor diabetes control and diabetes related complications, making diabetes control more challenging and difficult.</p>\",\"PeriodicalId\":19972,\"journal\":{\"name\":\"Patient preference and adherence\",\"volume\":\"18 \",\"pages\":\"1939-1948\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-09-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416907/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Patient preference and adherence\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/PPA.S463133\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Patient preference and adherence","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/PPA.S463133","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Prevalence and Impact of Psychological Disorders on Pharmacotherapy of Diabetic Patients in Low Resource Settings: A Prospective Assessment in Primary Healthcare Settings.
Background: Prevalence of psychological disorders among individuals with diabetes is significantly higher as compared to the general population.
Aim: This study aimed to assess the prevalence and impact of psychological disorders on pharmacotherapy of diabetes patients.
Methodology: This cross-sectional study was conducted at two primary care hospitals in Pakistan from April to June 2023. The nine-item Patient Health Care Questionnaire (PHQ-9) scale was used to assess depression in the study's population, and its effects on pharmacotherapy of diabetes. Chi-square test was used to evaluate relationship between ordinal variables/categorical variables and depression whereas; Student's t-test was used to assess the relationship between numerical variables with depression.
Results: A total of 320 patients were assessed, comprising 120 (37.5%) males and 200 (62.5%) females, with a mean age of 52.5 (SD±11.8) years. The average duration of diabetes is 7.0 (SD±5.4). The average PHQ-9 score was 8.3 (SD±5.5). Depression was found to be prevalent in 43.7% of the study population. Gender (female) (p-value 0.002), advanced age (p-value 0.002), lower income (p-value 0.001), education levels (p-value 0.001), longer duration of diabetes (p-value 0.001), poor diabetes control according to BSR value (p-value 0.001), usage of injectable insulin (p-value 0.005), and concomitant diseases (p-value 0.001) were found to be independently linked with depression. Significant association was observed between depression and treatment adherence (p-value 0.0025), number of missed doses (p-value 0.045), and difficulty in diabetes management (p-value 0.0015).
Conclusion: Our study highlights significant prevalence of depression in study population and the prevalent depression negatively impacts on treatment adherence. It also revealed that depression complicates diabetes management resulting in poor medication adherence, poor diabetes control and diabetes related complications, making diabetes control more challenging and difficult.
期刊介绍：
Patient Preference and Adherence is an international, peer reviewed, open access journal that focuses on the growing importance of patient preference and adherence throughout the therapeutic continuum. The journal is characterized by the rapid reporting of reviews, original research, modeling and clinical studies across all therapeutic areas. Patient satisfaction, acceptability, quality of life, compliance, persistence and their role in developing new therapeutic modalities and compounds to optimize clinical outcomes for existing disease states are major areas of interest for the journal.
As of 1st April 2019, Patient Preference and Adherence will no longer consider meta-analyses for publication.
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