加拿大青光眼患病率:2016-2019 年加拿大健康措施调查结果。

IF 3.3 4区 医学 Q1 OPHTHALMOLOGY
Ya-Ping Jin, Kiko Zi Yi Huang, Qingqing K Zhao, Graham E Trope, Yvonne M Buys, Sherif El-Defrawy, Peng Yan, Michael H Brent, Ziad Butty
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引用次数: 0

摘要

目的:根据自我报告和测试数据(包括倍频技术验光法(FDT)、视神经垂直杯盘比(CDR)、眼压(IOP)和青光眼药物使用情况)估算加拿大青光眼患病率:横断面调查。参与者:2016-2019 年加拿大健康措施调查中年龄在 40-79 岁之间的 2,600-4,100 名参与者,其信息来自自我报告、CDR、FDT 和 IOP:青光眼的定义是自我报告、CDR≥0.7或FDT失败。结合CDR、FDT、眼压和青光眼药物的使用情况,进一步将参与者分为明确的青光眼(FDT失败且CDR≥0.7)或疑似青光眼(仅CDR≥0.7,仅FDT失败,或仅眼压>21 mmHg,或FDT、CDR和眼压值 "正常 "但使用青光眼药物)。分析中使用了调查权重:利用自我报告的青光眼患病率为 2.5%(95% 置信区间 [CI] 1.7%-3.3%),仅 CDR ≥ 0.7 的患病率为 3.0%(95% 置信区间 [CI] 2.1%-3.9%),仅 FDT 失败的患病率为 10.3%(7.8%-12.8%)。合并检测数据后,确诊青光眼的患病率为 0.7%(95% CI 0.3%-1.1%),疑似青光眼的患病率为 16.3%(95% CI 13.2%-19.4%)。在疑似青光眼患者中,44.4%患有眼压过高(OHT,平均眼压 22.8 mmHg),6.8%使用青光眼药物。2.4%的 OHT 患者眼压≥28 mmHg,但没有人使用青光眼药物。37.5%患有明确青光眼的加拿大人不知道自己患有青光眼:结论:40-79 岁加拿大人中青光眼的发病率在 0.7% 到 10.3% 之间,具体取决于所使用的定义。16.3%的加拿大人被称为 "青光眼疑似患者"。在确诊患有青光眼的加拿大人中,有近 40% 的人不知道自己患有青光眼。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of glaucoma in Canada: results from the 2016-2019 Canadian Health Measures Survey.

Objective: To estimate the prevalence of glaucoma in Canada based on self-reports and test data, including Frequency Doubling Technology Perimetry (FDT), optic nerve vertical cup-to-disc ratio (CDR), intraocular pressure (IOP), and use of glaucoma medications.

Design: Cross-sectional survey.

Participants: 2,600-4,100 participants aged 40-79 in the Canadian Health Measures Survey 2016-2019 with available information from self-report, CDR, FDT, and IOP.

Methods: Glaucoma was defined by self-reports, CDR ≥ 0.7 only, or failed FDT only. Incorporating results of CDR, FDT, IOP, and use of glaucoma medications, participants were further classified as definite glaucoma (failed FDT and CDR ≥ 0.7) or glaucoma suspects (CDR ≥ 0.7 only, failed FDT only, or IOP > 21 mmHg only, or "normal" values of FDT, CDR, and IOP but used glaucoma medications). Survey weights were used in analyses.

Results: The glaucoma prevalence was 2.5% (95% confidence interval [CI] 1.7%-3.3%) utilizing self-reports, 3.0% (95% CI 2.1%-3.9%) by CDR ≥ 0.7 only and 10.3% (7.8%-12.8%) with failed FDT only. Merging test data, the prevalence of definite glaucoma was 0.7% (95% CI 0.3%-1.1%) and the prevalence of suspected glaucoma was 16.3% (95% CI 13.2%-19.4%). Among the patients suspected of having glaucoma, 44.4% had ocular hypertension (OHT, mean IOP 22.8 mmHg) and 6.8% used glaucoma medications. IOP ≥28 mmHg was found in 2.4% of OHT individuals, and none used glaucoma medications.37.5% of Canadians with definite glaucoma were unaware they had glaucoma.

Conclusions: Glaucoma prevalence in Canadians aged 40-79 varied between 0.7% and 10.3% depending on definition used. 16.3% of Canadians were labeled "glaucoma suspects". Nearly 40% of Canadians with definite glaucoma were unaware of having glaucoma.

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来源期刊
CiteScore
3.20
自引率
4.80%
发文量
223
审稿时长
38 days
期刊介绍: Official journal of the Canadian Ophthalmological Society. The Canadian Journal of Ophthalmology (CJO) is the official journal of the Canadian Ophthalmological Society and is committed to timely publication of original, peer-reviewed ophthalmology and vision science articles.
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