[多囊卵巢综合征:新的和有前途的治疗方法]。

D M Gasieva, E V Sheremetyeva, M F Kalashnikova, F Kh Dzgoeva, E T Alborova
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引用次数: 0

摘要

多囊卵巢综合症(PCOS)是一种由遗传、荷尔蒙和表观遗传因素引起的多基因内分泌失调症。治疗多囊卵巢综合症的重要性在于其发病率,约有 10% 至 13% 的女性患有此病,而且相关的健康问题会对女性的生活产生负面影响,包括不孕症、高雄激素的皮肤病表现(如多毛症和痤疮)、心血管病变、代谢紊乱和心理情感障碍。目前,人们提出了许多关于这种疾病发展的理论,并由此提出了影响和治疗这种疾病的方法。根据俄罗斯联邦卫生部的临床建议,改变患者的生活方式是综合治疗的基础。我们分析了来自 PubMed、Nature Reviews、Oxford Academic、Clinical Nutrition、EJOG、ScienceDirect 和 MDPI 的约 60 篇有关治疗多囊卵巢综合症的各种饮食方法的文章。事实证明,地中海饮食、DASH 饮食、生酮饮食和低碳水化合物饮食效果最好。此外,还需要在女性饮食中添加维生素 D、E、叶酸、钙、各种益生元和益生菌。目前,使用肌醇和 GPP-1 正在成为治疗多囊卵巢综合症的一种很有前景的方法。根据分析结果,饮食疗法对人体测量和生化指标有积极影响。根据分析结果,饮食疗法对人体测量和生化指标有积极影响。在治疗多囊卵巢综合症时,必须考虑每位患者的个体特征,而不能仅仅依赖药物治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Polycystic ovary syndrome: new and promising treatment methods].

Polycystic Ovary Syndrome (PCOS) - is a polygenic endocrine disorder caused by genetic, hormonal, and epigenetic factors. The importance of addressing PCOS lies in its prevalence, affecting approximately 10 to 13% of women, as well as the associated health conditions that can have a negative impact on women's lives, including infertility, dermatological manifestations of hyperandrogenism (such as hirsutism and acne), cardiovascular pathologies, metabolic disorders, and psychoemotional disorders. Currently, many theories of the development of this disease have been proposed, and as a consequence of methods of influencing and treating it. According to the clinical recommendations of the Ministry of Health of the Russian Federation, modifying the patient's lifestyle forms the basis of comprehensive therapy. We have analyzed about 60 articles on various dietary approaches to the treatment of PCOS, sourced from PubMed, Nature Reviews, Oxford Academic, Clinical Nutrition, EJOG, ScienceDirect, and MDPI. The Mediterranean diet, the DASH diet, the ketogenic diet and the low-carb diet have proven themselves the best. Also, it's necessary to add vitamin D, E, folic acid, calcium, various pro- and prebiotics to a woman's diet. Currently, the use of inositol and GPP-1 is becoming a promising method of PCOS therapy. According to the results of the analysis, a positive effect of diet therapy on the anthropometric and biochemical parameters was noted. Based on the analysis, a positive effect of diet therapy on anthropometric and biochemical parameters has been observed. It is crucial to consider the individual characteristics of each patient and not rely solely on drug therapy when approaching the treatment of PCOS.

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