母体代谢健康和营养对子代 β 细胞质量的甜点调控

4区生物学 Q3 Medicine

Advances in Anatomy Embryology and Cell Biology Pub Date : 2024-01-01 DOI:10.1007/978-3-031-62232-8_7

Grace Chung, Alicia Wong, Tracy Her, Emilyn U Alejandro

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引用次数: 0

摘要

孕期母体的营养和代谢健康状况是影响后代终生健康轨迹的关键因素。子宫内特定发育时期的营养变化可导致胰腺β细胞等组织的功能变化，使这些组织日后易患代谢性疾病和2型糖尿病。本章将重点讨论妊娠并发症和妊娠期营养改变对后代胰岛β细胞质量和功能的不良影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Sweet Spot Regulation of Maternal Metabolic Health and Nutrition on β-Cell Mass in the Offspring.

Maternal nutrition and metabolic health status during pregnancy are critical factors that shape the life-long health trajectory of offspring. Altered nutrition during specific times of development in utero can lead to functional changes in tissues such as the pancreatic β-cells, predisposing those tissues to metabolic diseases and Type 2 diabetes that manifest later in life. This chapter will focus on the role of pregnancy complications with altered nutrition during gestation in the maladaptive programming of β-cell mass and function in the offspring.

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来源期刊

Advances in Anatomy Embryology and Cell Biology 生物-发育生物学

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： "Advances in Anatomy, Embryology and Cell Biology" presents critical reviews on all topical fields of normal and experimental anatomy including cell biology. The multi-perspective presentation of morphological aspects of basic biological phenomen in the human constitutes the main focus of the series. The contributions re-evaluate the latest findings and show ways for further research.