前路颈椎椎间盘切除术和融合术治疗钳形颈椎病:一项单中心回顾性研究。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Xinyu Zhang, Baogan Peng, Zengbiao Ma, Bing Wu, Chunyu Liu, Yongchao Li
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引用次数: 0

摘要

背景:颈椎脊髓前后压迫通常被称为钳形颈椎病(p-CSM),一般建议进行手术治疗,但由于单一的前路或后路手术不能有效解除对侧压迫,联合手术可能会造成创伤和影响颈椎功能等相关问题,因此在手术方式的选择上存在一定争议:目的:探讨单一前路颈椎椎间盘切除和融合术(ACDF)治疗 p-CSM 的可行性和适应症:收集了2019年至2022年在一家中心接受ACDF治疗的21例p-CSM患者的数据。采用日本骨科协会(JOA)评分系统评估神经状态。放射学参数包括手术前后椎管所占空间百分比、颈椎矢状位Cobb角和脊髓横截面积。此外,还观察了并发症和脊髓压迫率。对减压效果与各种预后因素之间的相关性进行了统计分析:平均随访时间为(24.1±3.55)个月。平均 JOA 评分明显提高,平均痊愈率为 65.88±8.97%。融合率令人满意。相关分析显示,手术节段数和年龄是减压效果的重要预测因素。术后脊髓功能没有进一步恶化:ACDF在神经功能恢复、放射学参数、融合率和并发症方面是治疗钳形脊髓压迫的有效方法,尤其适用于年龄小于60岁的单手术节段患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anterior Cervical Discectomy and Fusion for the Treatment of Pincer Cervical Spondylotic Myelopathy: A Single-Center Retrospective Study.

Background: Anterior and posterior compression of the cervical spinal cord is usually called pincer cervical spondylotic myelopathy (p-CSM), and surgery is generally recommended; however, there is some controversy about the choice of surgical approach because single anterior or posterior surgery cannot effectively relieve contralateral compression, and combined surgery may cause problems related to trauma and effects on cervical spine function.

Objective: To investigate the feasibility and indications of single anterior cervical discectomy and fusion (ACDF) for the treatment of p-CSM.

Methods: The data of 21 p-CSM patients who were treated with ACDF at a single center from 2019 to 2022 were collected. Neurologic status was evaluated by the Japanese Orthopedic Association scoring system. The radiologic parameters included the percentage of space occupied by the spinal canal, the cervical sagittal Cobb angle, and the cross-sectional area of the spinal cord before and after the operation. Complications and spinal cord compression rates were also observed. Correlations between the decompressive effects and various prognostic factors were statistically analyzed.

Results: The mean follow-up period was 24.1 ± 3.55 months. The average Japanese Orthopedic Association score significantly increased, with a mean recovery rate of 65.88 ± 8.97%. The fusion rate was satisfactory. Correlation analysis revealed that the number of operation segments and age were important predictors of decompressive effects. There was no further deterioration of spinal cord function after the operation.

Conclusions: ACDF is an effective method for treating pincer spinal cord compression in terms of neurologic recovery, radiologic parameters, fusion rates, and complications, especially for patients younger than 60 years of age with single operative segments.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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