Celina Vieira de Albuquerque, Mylena da Silva Andrade, Marina Sereno de Freitas, Patrícia Gonzaga Paulino, Huarrisson Azevedo Santos, Paulo de Tarso Landgraf Botteon
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引用次数: 0
摘要
马螺旋体病(EP)和马粒细胞无形体病(EGA)是一种影响马匹的疾病,由伊科蜱传播,会引起非特异性发热综合征。马螺旋体病在巴西呈地方性流行,大多数马处于流行稳定期。对巴西马匹进行的血清学和分子研究显示,马匹体内存在噬细胞嗜血阿纳疟原虫,但这种感染的临床意义尚未确定。本研究旨在评估在里约热内卢大都会中区出现临床表现的马匹中,卡巴贝氏虫、马丝虫和噬细胞嗜血杆菌作为病原体的重要性。共对 45 匹有临床症状的马进行了 DNA 提取和 qPCR 检测。在所有出现临床症状的马匹中均未发现噬细胞嗜血阿纳疟原虫、立氏新立克次体(Neorickettsia risticii)和汉尼马丝菌(Theileria haneyi),但62.2%的马匹至少感染了一种EP病原体。马丝虫是最常见的致病菌(35.5%),其次是混合感染(15.5%)和卡巴列氏菌(11.2%)。这些结果表明,噬细胞嗜血杆菌在该地区的临床意义不大,而EP则经常出现在有症状的马匹身上,是疑似病例的重要鉴别诊断依据。
Significance of Anaplasma phagocytophilum, Babesia caballi, and Theileria equi as etiologic agents in horses with clinical manifestations from the metropolitan area of Rio De Janeiro, Brazil.
Equine Piroplasmosis (EP) and Equine Granulocytic Anaplasmosis (EGA) are diseases that affect horses, transmitted by ixodid ticks, causing a nonspecific febrile syndrome. Equine Piroplasmosis is endemic in Brazil, and most horses are in enzootic stability. Serological and molecular studies carried out on horses in Brazil have shown the presence of Anaplasma phagocytophilum, however, the clinical relevance of this infection has not yet been established. The present study aims to evaluate the importance of Babesia caballi, Theileria equi, and A. phagocytophilum as etiological agents in horses with clinical manifestations suggestive of these diseases in the metropolitan mesoregion of Rio de Janeiro. A total of 45 animals with clinical signs were submitted to DNA extraction followed by qPCR test. Anaplasma phagocytophilum, Neorickettsia risticii and Theileria haneyi were not found in any of the horses with clinical signs, however 62.2% were infected with at least one agent of EP. Theileria equi was the most frequent etiologic agent (35.5%), followed by coinfection (15.5%) and B. caballi (11.2%). These results suggest that A. phagocytophilum has minor clinical importance in the region, while EP is frequently found in symptomatic horses, representing an important differential diagnosis in suspected cases.
期刊介绍:
Tropical Animal Health and Production is an international journal publishing the results of original research in any field of animal health, welfare, and production with the aim of improving health and productivity of livestock, and better utilisation of animal resources, including wildlife in tropical, subtropical and similar agro-ecological environments.