Andrew Moore, Ben Lewis, Hugh Farrior, Jesse Hinckley, Sara Jo Nixon, Devika Bhatia
{"title":"青春期前对物质的熟悉程度对后续使用的影响:青少年大脑认知发展样本中潜在类别的风险纵向分析。","authors":"Andrew Moore, Ben Lewis, Hugh Farrior, Jesse Hinckley, Sara Jo Nixon, Devika Bhatia","doi":"10.1080/10826084.2024.2403109","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Predicting substance use in adolescence is a difficult yet important task in developing effective prevention. We aim to extend previous findings on the linear associations between familiarity with (knowledge of) substances in childhood and subsequent substance use in adolescence through a latent class analysis (LCA) to create risk profiles based on substance familiarity.</p><p><strong>Method: </strong>Using the ABCD Study<sup>®</sup> sample, we conducted an LCA using 18 binary substance familiarity variables (<i>n</i> = 11,694 substance-naïve youth). Complementary analyses investigated the relationship between LCA groups and (1) longitudinal use, (2) use initiation, and (3) early use.</p><p><strong>Results: </strong>The optimal LCA resulted in a four-class solution: Naïve, Common, Uncommon, and Rare, with each group increasing in both the number and rarity of known substances. Analysis 1 revealed an increased risk in use over time among both the Uncommon and Rare groups (ORs = 2.08 and 5.55, respectively, <i>p</i>'<i>s</i> < 0.001) compared to the Common group. Analysis 2 observed a decreased risk for initiation between the Naïve and Common groups (OR = 0.61, <i>p</i> = 0.009); however, the Uncommon and Rare groups were at an increased risk compared to the Common group (ORs = 2.08 and 3.42, respectively, <i>p</i>'<i>s</i> < 0.001). Analysis 3 found an increased risk of early use between the Common and Uncommon groups (OR = 1.92, <i>p</i> < 0.001) with a similar trend between the Common and Rare groups (OR = 1.90, <i>p</i> = 0.06).</p><p><strong>Conclusion: </strong>These results highlight distinct risk profiles for adolescent substance use based on substance familiarity in middle childhood. Current work could be applied as an early screening tool for clinicians to identify those at risk for adolescent substance use.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of Pre-Adolescent Substance Familiarity on Subsequent Use: Longitudinal Analysis of Risk by Latent Classes in the Adolescent Brain Cognitive Development Sample.\",\"authors\":\"Andrew Moore, Ben Lewis, Hugh Farrior, Jesse Hinckley, Sara Jo Nixon, Devika Bhatia\",\"doi\":\"10.1080/10826084.2024.2403109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Predicting substance use in adolescence is a difficult yet important task in developing effective prevention. We aim to extend previous findings on the linear associations between familiarity with (knowledge of) substances in childhood and subsequent substance use in adolescence through a latent class analysis (LCA) to create risk profiles based on substance familiarity.</p><p><strong>Method: </strong>Using the ABCD Study<sup>®</sup> sample, we conducted an LCA using 18 binary substance familiarity variables (<i>n</i> = 11,694 substance-naïve youth). Complementary analyses investigated the relationship between LCA groups and (1) longitudinal use, (2) use initiation, and (3) early use.</p><p><strong>Results: </strong>The optimal LCA resulted in a four-class solution: Naïve, Common, Uncommon, and Rare, with each group increasing in both the number and rarity of known substances. Analysis 1 revealed an increased risk in use over time among both the Uncommon and Rare groups (ORs = 2.08 and 5.55, respectively, <i>p</i>'<i>s</i> < 0.001) compared to the Common group. Analysis 2 observed a decreased risk for initiation between the Naïve and Common groups (OR = 0.61, <i>p</i> = 0.009); however, the Uncommon and Rare groups were at an increased risk compared to the Common group (ORs = 2.08 and 3.42, respectively, <i>p</i>'<i>s</i> < 0.001). Analysis 3 found an increased risk of early use between the Common and Uncommon groups (OR = 1.92, <i>p</i> < 0.001) with a similar trend between the Common and Rare groups (OR = 1.90, <i>p</i> = 0.06).</p><p><strong>Conclusion: </strong>These results highlight distinct risk profiles for adolescent substance use based on substance familiarity in middle childhood. Current work could be applied as an early screening tool for clinicians to identify those at risk for adolescent substance use.</p>\",\"PeriodicalId\":22088,\"journal\":{\"name\":\"Substance Use & Misuse\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Substance Use & Misuse\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/10826084.2024.2403109\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Substance Use & Misuse","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10826084.2024.2403109","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PSYCHIATRY","Score":null,"Total":0}
Impact of Pre-Adolescent Substance Familiarity on Subsequent Use: Longitudinal Analysis of Risk by Latent Classes in the Adolescent Brain Cognitive Development Sample.
Background: Predicting substance use in adolescence is a difficult yet important task in developing effective prevention. We aim to extend previous findings on the linear associations between familiarity with (knowledge of) substances in childhood and subsequent substance use in adolescence through a latent class analysis (LCA) to create risk profiles based on substance familiarity.
Method: Using the ABCD Study® sample, we conducted an LCA using 18 binary substance familiarity variables (n = 11,694 substance-naïve youth). Complementary analyses investigated the relationship between LCA groups and (1) longitudinal use, (2) use initiation, and (3) early use.
Results: The optimal LCA resulted in a four-class solution: Naïve, Common, Uncommon, and Rare, with each group increasing in both the number and rarity of known substances. Analysis 1 revealed an increased risk in use over time among both the Uncommon and Rare groups (ORs = 2.08 and 5.55, respectively, p's < 0.001) compared to the Common group. Analysis 2 observed a decreased risk for initiation between the Naïve and Common groups (OR = 0.61, p = 0.009); however, the Uncommon and Rare groups were at an increased risk compared to the Common group (ORs = 2.08 and 3.42, respectively, p's < 0.001). Analysis 3 found an increased risk of early use between the Common and Uncommon groups (OR = 1.92, p < 0.001) with a similar trend between the Common and Rare groups (OR = 1.90, p = 0.06).
Conclusion: These results highlight distinct risk profiles for adolescent substance use based on substance familiarity in middle childhood. Current work could be applied as an early screening tool for clinicians to identify those at risk for adolescent substance use.
期刊介绍:
For over 50 years, Substance Use & Misuse (formerly The International Journal of the Addictions) has provided a unique international multidisciplinary venue for the exchange of original research, theories, policy analyses, and unresolved issues concerning substance use and misuse (licit and illicit drugs, alcohol, nicotine, and eating disorders). Guest editors for special issues devoted to single topics of current concern are invited.
Topics covered include:
Clinical trials and clinical research (treatment and prevention of substance misuse and related infectious diseases)
Epidemiology of substance misuse and related infectious diseases
Social pharmacology
Meta-analyses and systematic reviews
Translation of scientific findings to real world clinical and other settings
Adolescent and student-focused research
State of the art quantitative and qualitative research
Policy analyses
Negative results and intervention failures that are instructive
Validity studies of instruments, scales, and tests that are generalizable
Critiques and essays on unresolved issues
Authors can choose to publish gold open access in this journal.