高血压患者饮用咖啡和茶与痴呆症风险之间的关系:一项前瞻性队列研究。

IF 3.8 2区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Bo Wang, Ting Ma, Lingling Yang, Shulan He, Jiangping Li, Xian Sun
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引用次数: 0

摘要

许多研究表明,喝咖啡和茶可能与高血压和痴呆症的风险有关。关于咖啡和茶对高血压患者痴呆症风险影响的研究还很有限。本研究旨在通过英国生物库中的 453,913 名参与者,利用 Cox 比例风险模型确定高血压人群饮用咖啡和茶与痴呆症发病风险之间的关系。我们的研究结果表明,高血压患者全因痴呆症的发病风险分别与咖啡和茶的饮用量呈 "J "形和 "U "形关系。每天喝 0.5-1 杯咖啡或 4-5 杯茶的高血压患者患痴呆症的风险最低。在高血压人群中,每日咖啡因摄入量与患全因痴呆症和血管性痴呆症的风险呈 "U "型关系。此外,与非高血压人群相比,高血压患者的咖啡和茶饮用量与全因痴呆和血管性痴呆风险之间更有可能存在明显的关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association between coffee and tea consumption and the risk of dementia in individuals with hypertension: a prospective cohort study.

Many studies have shown that drinking coffee and tea may be associated with the risk of hypertension and dementia. Limited research exists on their impact on dementia risk in hypertensive patients. This study aimed to determine the association between coffee and tea consumption and the risk of dementia development in hypertensive population by utilizing Cox proportional risk modeling with 453,913 participants from a UK biobank. Our findings reveal a J-shaped and U-shaped association between the risk of all-cause dementia and the consumption of coffee and tea respectively in hypertensive people. The hypertensive patients who drink 0.5-1 cup of coffee or 4-5 cups of tea per day have the lowest risk of dementia. A U-shaped relationship was observed between daily caffeine consumption and the risk of developing all-cause dementia and vascular dementia in the hypertensive population. Furthermore, the significant association between the amount of coffee and tea consumed and the risk of all-cause and vascular dementia were more likely to be found in hypertensive patients than in the non-hypertensive population.

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来源期刊
Scientific Reports
Scientific Reports Natural Science Disciplines-
CiteScore
7.50
自引率
4.30%
发文量
19567
审稿时长
3.9 months
期刊介绍: We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections. Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021). •Engineering Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live. •Physical sciences Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics. •Earth and environmental sciences Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems. •Biological sciences Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants. •Health sciences The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.
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