NMOSD 和 MOGAD 有哪些新内容？

IF 2.8 4区医学 Q2 CLINICAL NEUROLOGY

Revue neurologique Pub Date : 2024-11-01 DOI:10.1016/j.neurol.2024.08.004

R. Marignier

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引用次数: 0

摘要

在这篇微型综述中，我们将重点关注神经脊髓炎视网膜频谱疾病（NMOSD）和髓鞘少突胶质细胞糖蛋白抗体相关疾病（MOGAD）领域的新进展。我们首先介绍了 MOGAD 的拟议标准，并评估了这些标准的影响和潜在局限性，重点关注仅在脑脊液中检测出 MOG 抗体阳性的亚组患者。然后，我们简要介绍了目前对所谓 "双血清阴性 "NMOSD 群体的认识，包括其病理学、临床、生物学和影像学特征，以及该领域尚未满足的需求。最后一部分是关于 NMSOD 和 MOGAD 急性治疗的现状和未来。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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What's new in NMOSD and MOGAD?

In this mini-review, we focus on novelties in the field of neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD). We first describe the proposed criteria for MOGAD and evaluate their impact and potential limitations, with a highlight on the subgroups of patients tested MOG-antibody positive only in the cerebrospinal fluid. We then propose a brief state of the art on the current knowledge on the so-call “double seronegative” NMOSD group, regarding nosology, clinical, biological and imaging features and the unmet need in this field. The last part is dedicating to the present and future of acute treatment in NMSOD and MOGAD.

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来源期刊

Revue neurologique 医学-临床神经学

CiteScore

4.80

自引率

0.00%

发文量

598

审稿时长

55 days

期刊介绍： The first issue of the Revue Neurologique, featuring an original article by Jean-Martin Charcot, was published on February 28th, 1893. Six years later, the French Society of Neurology (SFN) adopted this journal as its official publication in the year of its foundation, 1899. The Revue Neurologique was published throughout the 20th century without interruption and is indexed in all international databases (including Current Contents, Pubmed, Scopus). Ten annual issues provide original peer-reviewed clinical and research articles, and review articles giving up-to-date insights in all areas of neurology. The Revue Neurologique also publishes guidelines and recommendations. The Revue Neurologique publishes original articles, brief reports, general reviews, editorials, and letters to the editor as well as correspondence concerning articles previously published in the journal in the correspondence column.