不同胸腔镜切除术治疗I期非小细胞肺癌的临床效果对比分析

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Hao Jiang, Tong Wu, Peng Qie, Huien Wang, Baoxin Zhang
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引用次数: 0

摘要

目的比较和分析胸腔镜肺叶切除术和肺段切除术对 I 期非小细胞肺癌(NSCLC)的临床效果:这是一项回顾性研究。将沧州市人民医院2019年12月至2022年1月收治的80例I期NSCLC患者随机分为分段切除组和肺叶切除组,每组40例。围绕围手术期指标、最大通气量(MVV)、用力肺活量(FVC)、第一秒用力呼气容积(FEV1)、术后疼痛VAS评分及并发症等进行进一步对比分析:结果:两组在切除淋巴结数量和拔管时间上无明显差异(P>0.05)。与肺叶切除术组相比,分段切除术组的手术时间更长,术中失血量更少,住院时间更短(P0.05)。同时,分段切除组在术后 1 d、3 d 和 5 d 的 VAS 评分明显低于肺叶切除组(P 结论:与肺叶切除术相比,胸腔镜下肺段切除术治疗I期NSCLC效果更好,出血少、疼痛轻,可减轻肺功能损伤,减少术后并发症,有利于改善患者预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative analysis of the clinical effects of different thoracoscopic resection in the treatment of Stage I Non-Small Cell Lung Cancer.

Objective: To compare and analyze the clinical effects of thoracoscopic lobectomy and segmentectomy in stage I non-small cell lung cancer (NSCLC).

Method: This was a retrospective study. Eighty patients with stage I NSCLC treated in Cangzhou People's Hospital from December 2019 to January 2022 were randomly divided into the segmentectomy group and lobectomy group, with 40 cases in each group. Further comparative analysis was carried out focusing on perioperative indexes, maximum ventilation volume (MVV), forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), VAS score of postoperative pain and complications.

Result: There was no significant difference in the number of dissected lymph nodes and extubation time between the two groups (p>0.05). The operation time was longer, while intraoperative blood loss was less and the stay of stay in hospital was shorter in the segmentectomy group significantly than those in the lobectomy group (p<0.05). Furthermore, no significant difference was observed in MVV%, FVC% and FEV1% between the two groups before operation (p>0.05). Meanwhile, the segmentectomy group had evidently lower VAS scores at 1 d, 3 d and 5 d postoperatively than those in the lobectomy group (p<0.05). Besides, there was a much lower total incidence of complications in the segmentectomy group than that in the lobectomy group (p<0.05).

Conclusion: Compared with lobectomy, thoracoscopic segmentectomy is more effective in the treatment of stage I NSCLC, with less bleeding and mild pain, which can alleviate pulmonary function injury and reduce postoperative complications that is conducive to the improved prognosis of patients.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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