活性氧液（Blue®m）作为根管冲洗剂对粪肠球菌的影响

IF 1.4 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Oral health & preventive dentistry Pub Date : 2024-09-12 DOI:10.3290/j.ohpd.b5740308

Reem Barakat, Rahaf Almohareb, Arwa Alshahri, Nardeen Khawaji, Sarah Almufrij, Dhuha Alsuwaid, Fatma Alshehri

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引用次数: 0

摘要

目的：与次氯酸钠（NaOCl）相比，评估新型活性氧液（Blue®m）作为根管冲洗剂对粪肠球菌的抗菌效果：选取 45 颗拔出的单瓣人类牙齿，对其进行根管预备、高压灭菌和粪肠球菌污染。标本被随机分为三组：A 组作为阴性对照，接受生理盐水灌洗（n =；15）；B 组接受 5.25% NaOCl 灌洗（n =；15）；C 组接受 10 mL Blue®m 灌洗（n =；15）。在灌洗前后对根管进行微生物取样。计算灌洗前和灌洗后菌落形成单位（CFU/mL）的差异。数据分析采用单因素方差分析，然后进行事后 Tukey 检验。显著性水平设定为 5%：结果：与生理盐水相比，Blue®m 在统计学上明显减少了细菌量（p =；0.009），但 NaOCl 的效果最好，优于两者（p 0.0001）：结论：用蓝®m 冲洗对粪肠球菌有抗菌效果，但不如 NaOCl 有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Effect of Active Oxygen Fluid (Blue®m) as a Root Canal Irrigant Against Enterococcus Faecalis.

Purpose: To evaluate the antimicrobial effect of a new active oxygen fluid (Blue®m) as a root canal irrigant against Enterococcus faecalis compared to sodium hypochlorite (NaOCl).

Material and methods: Forty-five extracted single-canaled human teeth were selected, received root canal preparation, autoclaved, and contaminated with Enterococcus faecalis. The specimens were randomly allocated into three groups: Group (A) served as the negative control, receiving irrigation with saline (n = 15); Group (B) was irrigated with 5.25% NaOCl (n = 15); and Group (C) was irrigated with 10 mL of Blue®m (n = 15). Microbial sampling from the root canals was performed before and after irrigation. The difference between the pre-irrigation and post-irrigation colony-forming units (CFU/mL) was calculated. The data was analysed using a one-way ANOVA followed by post-hoc Tukey tests. The significance level was set at 5%.

Results: Blue®m statistically significantly reduced the bacterial load compared to saline (p = 0.009), but NaOCl was most effective, outperforming both (p 0.0001).

Conclusion: Irrigation with Blue®m demonstrated antibacterial efficacy against Enterococcus faecalis, but it was not as effective as NaOCl.

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来源期刊

Oral health & preventive dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Clinicians, general practitioners, teachers, researchers, and public health administrators will find this journal an indispensable source of essential, timely information about scientific progress in the fields of oral health and the prevention of caries, periodontal diseases, oral mucosal diseases, and dental trauma. Central topics, including oral hygiene, oral epidemiology, oral health promotion, and public health issues, are covered in peer-reviewed articles such as clinical and basic science research reports; reviews; invited focus articles, commentaries, and guest editorials; and symposium, workshop, and conference proceedings.