Millmerranones G，一种从红树林真菌 Aspergillus sp. GXIMD 03004 中分离出来的美拉皮烯。

IF 1.9 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2024-09-17 DOI:10.1080/14786419.2024.2402460

Guang-Ping Cao, Guo-Qiang Huang, Guang-Ying Chen, Xiang-Xi Yi, Xue-Sheng Wang, Feng-Jiao Wei, Cai-Qiong Zhu, Cheng-Hai Gao, Yong-Hong Liu, Meng Bai

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引用次数: 0

摘要

从采集自中国北部湾的红树林 Acanthus ilicifolius L.叶片中分离出的红树林源真菌 Aspergillus sp.通过全面解读核磁共振光谱和 HRESIMS 数据，确定了 1 的结构特征。利用实验和计算的 ECD 数据确定了 1 的绝对构型。对所有化合物的抗弧菌活性进行了评估，结果表明化合物 1 和 2 对 Harveyi 弧菌的活性较弱。

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Millmerranones G, a meroterpene isolated from a mangrove-derived fungus Aspergillus sp. GXIMD 03004.

One new meroterpene derivative, millmerranones G (1), and three known analogues (2-4) were identified from the mangrove-derived fungus Aspergillus sp. GXIMD 03004, which was isolated from the leaves of mangrove Acanthus ilicifolius L. collected from Beibu Gulf in China. The structure of 1 was characterised by a comprehensive interpretation of the NMR spectroscopic and HRESIMS data. The absolute configuration for 1 was established using experimental and calculated ECD data. The anti-Vibrio activities of all compounds were evaluated, the result showed that compounds 1 and 2 has weak activity against Vibrio harveyi.

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.